Ictal and interictal electric source imaging in pre-surgical evaluation: a prospective study

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
P SharmaS Beniczky

Abstract

Accurate localization of the epileptic focus is essential for surgical treatment of patients with drug-resistant epilepsy. Electric source imaging (ESI) is increasingly used in pre-surgical evaluation. However, most previous studies have analysed interictal (II) discharges. Prospective studies comparing the feasibility and accuracy of II and ictal (IC) ESI are lacking. We prospectively analysed long-term video-electroencephalography recordings (LTM) of patients admitted for pre-surgical evaluation. We performed ESI of II and IC signals using two methods, i.e. equivalent current dipole (ECD) and a distributed source model (DSM). LTM recordings employed the standard 25-electrode array (including inferior temporal electrodes). An age-matched template head model was used for source analysis. Results were compared with intracranial recordings, conventional neuroimaging methods [magnetic resonance imaging (MRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT)] and outcome at 1 year after surgery. A total of 87 consecutive patients were analysed. ECD gave a significantly higher proportion of patients with localized focal abnormalities (94%) compared with MRI (70%), PET (66%) and SPECT (64%). Agre...Continue Reading

References

Feb 11, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·J S Ebersole
Aug 28, 2001·Brain : a Journal of Neurology·F Rosenow, H Lüders
Dec 13, 2002·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Paul BoonJacques De Reuck
Dec 24, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G LantzC M Michel
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christoph M MichelRolando Grave de Peralta
Oct 29, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martine GavaretPatrick Chauvel
Aug 4, 2006·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martine GavaretPatrick Chauvel
Sep 5, 2006·Neuroreport·Sándor BeniczkyMartin Fabricius
Oct 19, 2007·Epilepsia·Chris PlummerMark Cook
Oct 7, 2011·Brain : a Journal of Neurology·Verena BrodbeckMargitta Seeck
Aug 1, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·Pierre MégevandMargitta Seeck
May 30, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Agustina M LascanoMargitta Seeck
Jan 29, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Mihai Dragos MălîiaSándor Beniczky
Oct 21, 2016·Seizure : the Journal of the British Epilepsy Association·Sándor BeniczkyPål Gunnar Larsson
Aug 6, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Margitta SeeckSándor Beniczky
Aug 26, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sándor BeniczkySusan T Herman
Oct 17, 2017·NeuroImage. Clinical·Willeke StaljanssensPieter van Mierlo

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Citations

Apr 26, 2019·Frontiers in Neurology·Christoph M Michel, Denis Brunet
Nov 9, 2019·F1000Research·Christoph BaumgartnerSusanne Pirker
Aug 6, 2019·Frontiers in Neurology·Pieter van MierloSerge Vulliemoz
Nov 3, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Bernd J VorderwülbeckeSerge Vulliemoz
Feb 21, 2021·Seizure : the Journal of the British Epilepsy Association·Ricardo Lutzky SauteJoao Pereira Leite
Mar 11, 2020·Seizure : the Journal of the British Epilepsy Association·Simone VespaRiëm El Tahry
May 12, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Amir G BaroumandSándor Beniczky
May 26, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Lorenzo RicciChristos Papadelis
Jun 29, 2021·Frontiers in Neuroscience·Lukas HeckerJürgen Kornmeier
Jul 31, 2021·Pediatric Neurology·Fernando N GalanRaj D Sheth

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