Ictal SPECT in patients with rapid eye movement sleep behaviour disorder

Brain : a Journal of Neurology
G MayerHermann Stefan

Abstract

Rapid eye movement sleep behaviour disorder is a rapid eye movement parasomnia clinically characterized by acting out dreams due to disinhibition of muscle tone in rapid eye movement sleep. Up to 80-90% of the patients with rapid eye movement sleep behaviour disorder develop neurodegenerative disorders within 10-15 years after symptom onset. The disorder is reported in 45-60% of all narcoleptic patients. Whether rapid eye movement sleep behaviour disorder is also a predictor for neurodegeneration in narcolepsy is not known. Although the pathophysiology causing the disinhibition of muscle tone in rapid eye movement sleep behaviour disorder has been studied extensively in animals, little is known about the mechanisms in humans. Most of the human data are from imaging or post-mortem studies. Recent studies show altered functional connectivity between substantia nigra and striatum in patients with rapid eye movement sleep behaviour disorder. We were interested to study which regions are activated in rapid eye movement sleep behaviour disorder during actual episodes by performing ictal single photon emission tomography. We studied one patient with idiopathic rapid eye movement sleep behaviour disorder, one with Parkinson's disease a...Continue Reading

References

Dec 1, 1990·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A J Beitz
May 12, 2006·Nature·Jun LuClifford B Saper
Jan 20, 2007·Brain : a Journal of Neurology·K Stiasny-KolsterG Mayer
Jan 20, 2007·Brain : a Journal of Neurology·Valérie Cochen De CockIsabelle Arnulf
Apr 7, 2007·Brain : a Journal of Neurology·B F BoeveH Braak
Jul 25, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ramalingam VetrivelanJun Lu
Jul 30, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Ronald B PostumaJacques Y Montplaisir
Jan 25, 2011·Neurobiology of Aging·T E ScammellJ M Siegel
Nov 16, 2011·Pflügers Archiv : European journal of physiology·Pierre-Hervé LuppiPatrice Fort
Dec 14, 2011·European Neurology·Nicholas-Tiberio EconomouClaudio L Bassetti
Dec 17, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Delphine OudietteIsabelle Arnulf
Jan 11, 2012·Journal of Neural Transmission·Chadwick W ChristineJill L Ostrem
Mar 2, 2012·Sleep·Christoph ScherflerBirgit Högl
Nov 24, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Olivier ClémentPierre-Hervé Luppi
Mar 19, 2013·Journal of Sleep Research·Gianina LucaUNKNOWN European Narcolepsy Network
Jun 27, 2013·Brain : a Journal of Neurology·Daniel García-LorenzoStéphane Lehericy
Jan 24, 2014·Neurology·Florian HoltberndJacques Montplaisir
Nov 13, 2014·Frontiers in Human Neuroscience·Lukas JaegerSpyros Kollias

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Citations

Nov 18, 2015·Annals of Neurology·Fabrizio De CarliLino Nobili
May 31, 2015·Brain : a Journal of Neurology·Yves Dauvilliers, Philippe Peigneux
Mar 26, 2016·Brain : a Journal of Neurology·Bradley F BoeveKejal Kantarci
Sep 28, 2015·Neuroscience and Biobehavioral Reviews·Carol P WeingartenNan-kuei Chen
Mar 21, 2015·Brain : a Journal of Neurology·Mark W Mahowald, Carlos H Schenck
Nov 25, 2017·Nature Reviews. Neurology·Birgit HöglAleksandar Videnovic
Jan 8, 2019·Journal of Sleep Research·Marion CléIsabelle Arnulf
Nov 13, 2019·Annals of Clinical and Translational Neurology·Yun ShenXiang Gao
Dec 15, 2016·Journal of Neurology, Neurosurgery, and Psychiatry·Anand TekriwalAviva Abosch
Nov 16, 2016·Current Neurology and Neuroscience Reports·Luigi Ferini-StrambiRomina Combi
Apr 22, 2018·Current Treatment Options in Neurology·Valérie Cochen De Cock
Oct 17, 2018·Frontiers in Neurology·Tayyabah YousafMarios Politis
Aug 7, 2019·Annals of Clinical and Translational Neurology·Elena AntelmiGiuseppe Plazzi
Aug 5, 2020·Journal of Sleep Research·Marie-Josèphe ChallamelPatricia Franco
Sep 1, 2018·Nature Reviews. Disease Primers·Yves DauvilliersBradley Boeve
Jan 22, 2018·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jesper JeppesenMichael Sommerauer

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