ID-CUBE direct analysis in real time high-resolution mass spectrometry and its capabilities in the identification of phenolic components from the green leaves of Bergenia crassifolia L

Rapid Communications in Mass Spectrometry : RCM
Elena S ChernetsovaGertrud E Morlock

Abstract

Bergenia crassifolia is a plant widely used in herbal medicine. Its chemical composition has been little studied, and no studies using high-resolution mass spectrometry (HRMS) have been performed. Its phenolic components are of particular interest, due to the interest in such compounds in medicine and cosmetics. The ID-CUBE, a simplified Direct Analysis in Real Time (DART) ion source, suitable for the fast MS analysis of liquids without complex sample preparation, offers a new method of studying extracts of such plant. Coupling the ID-CUBE with a high-resolution mass spectrometer can provide identification of extract components. Mass spectral conditions were optimized for model solutions of the flavonoid naringenin and used for the identification of phenolic compounds in green leaves extracts of Bergenia crassifolia. OpenSpot sample cards with a metal grid surface were used for sample introduction into the ID-CUBE ion source on an Obitrap mass spectrometer. The samples were applied as 5-μL aliquots of the extract onto the metal grid of the card. Sample ionization was stimulated in the ion source within 20 s by applying an electric current to the metal grid to thermally desorb the analytes into the gas flow of metastable helium ...Continue Reading

References

Jan 1, 1969·Journal of the Chemical Society. Perkin Transactions 1·E Haslam
Aug 10, 2002·Journal of Ethnopharmacology·L KokoskaT Vanek
Mar 26, 2005·Current Opinion in Neurology·Henrik Hagberg, Carina Mallard
Apr 15, 2005·Analytical Chemistry·Robert B CodyH Dupont Durst
Dec 24, 2005·Phytotherapy Research : PTR·S V PopovR G Ovodova
Oct 18, 2008·Journal of the American Society for Mass Spectrometry·Liguo SongJohn E Bartmess
Jun 7, 2011·Journal of Agricultural and Food Chemistry·Yusei KashimaMitsuo Miyazawa
Jul 14, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Tomas CajkaJana Hajslova
Jul 19, 2011·Rapid Communications in Mass Spectrometry : RCM·Elena S ChernetsovaGertrud E Morlock
Aug 16, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·S E EdisonL Parrales
Feb 24, 2012·Analytical and Bioanalytical Chemistry·Elena S ChernetsovaGertrud E Morlock

❮ Previous
Next ❯

Citations

Sep 17, 2013·Analytical and Bioanalytical Chemistry·Jürgen H Gross
Jan 11, 2013·Chemical Reviews·María Eugenia MongeFacundo M Fernández
Jul 30, 2014·Analytical and Bioanalytical Chemistry·Anastasia AlbertCarsten Engelhard
Dec 3, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Alexander N ShikovHildebert Wagner
Oct 17, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Daxin ChenJun Peng
Jan 1, 2016·Journal of Chromatography. a·André de VilliersHarald Pasch
Dec 23, 2015·Rapid Communications in Mass Spectrometry : RCM·Tim T Häbe, Gertrud E Morlock
Jul 15, 2015·Rapid Communications in Mass Spectrometry : RCM·Tim T Häbe, Gertrud E Morlock
Feb 28, 2014·Rapid Communications in Mass Spectrometry : RCM·Wilco F DuvivierMichel W F Nielen
Sep 24, 2015·Rapid Communications in Mass Spectrometry : RCM·Elena S Chernetsova, Gertrud E Morlock
Oct 20, 2012·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Alexander N ShikovBertalan Galambosi
Apr 20, 2014·Journal of Ethnopharmacology·Alexander N ShikovMichael Heinrich
Dec 17, 2014·Journal of the American Society for Mass Spectrometry·Jürgen H Gross
Aug 17, 2016·Rapid Communications in Mass Spectrometry : RCM·Wilco F DuvivierMichel W F Nielen
May 16, 2015·Mass Spectrometry Reviews·Tianyang GuoTianwei Tan
Jun 5, 2019·Journal of the American Society for Mass Spectrometry·Yi YouJacob T Shelley
Jun 5, 2014·European Journal of Mass Spectrometry·Jürgen H Gross
Sep 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Siyuan LuoChunbang Ding
Dec 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bhupendra KoulJun-O Jin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.