ID Learning Unit: Understanding and Interpreting Testing for Clostridium difficile

Open Forum Infectious Diseases
Daniel A Solomon, Danny A Milner

Abstract

Understanding and interpreting the molecular tests for Clostridium difficile is challenging because there are several different types of assays and most laboratories combine multiple tests in order to assess for presence of disease. This learning unit demonstrates the basic principles of each test along with its strengths and weaknesses, and illustrates how the tests are used in clinical practice.

References

Jan 27, 1994·The New England Journal of Medicine·C P KellyJ T LaMont
Feb 10, 2000·The New England Journal of Medicine·L KyneC P Kelly
Nov 28, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Andrew E SimorUNKNOWN SHEA Long-Term-Care Committee
Feb 8, 2003·Journal of Clinical Microbiology·Tracy D Wilkins, David M Lyerly
Feb 27, 2009·Journal of Clinical Microbiology·Frédéric BarbutCatherine Eckert
Jul 5, 2013·Clinical Microbiology Reviews·Carey-Ann D Burnham, Karen C Carroll
Aug 21, 2013·The Journal of Hospital Infection·D M GuerreroC J Donskey
Feb 8, 2014·Gastroenterology·Robert A Britton, Vincent B Young

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Citations

Mar 21, 2017·Revista de gastroenterología de México·A Rodríguez-VarónM Tobón-Trujillo
Jul 18, 2018·Journal of Intensive Care Medicine·Christopher C Battaglia, Kaye Hale
Jun 4, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Nikki N TranGregory A Eschenauer
Feb 28, 2019·Journal of Pharmacy Practice·Simon W Lam, Stephanie N Bass
Sep 8, 2020·Expert Review of Anti-infective Therapy·Andrew M PeseskiHeiko Konig

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Methods Mentioned

BETA
PCR
Assay
ELISA

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