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Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

Oncotarget

Apr 21, 2017

Hanadi M BaeissaFrances M G Pearl

Abstract

The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the consequences of that mutation both on the function of the affected protein and on the pathways in which that protein is involved. Protein dom...read more

Mentioned in this Paper

Biochemical Pathway
Positioning Attribute
Genome
Metastasis Suppressor Genes
Neoplasms
Tumor Lysis Syndrome
Src Homology Domains
Gene Mutation
Whole Exome Sequencing
Genomics
Paper Details
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Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

Oncotarget

Apr 21, 2017

Hanadi M BaeissaFrances M G Pearl

PMID: 28423505

DOI: 10.18632/oncotarget.15514

Abstract

The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the consequences of that mutation both on the function of the affected protein and on the pathways in which that protein is involved. Protein dom...read more

Mentioned in this Paper

Biochemical Pathway
Positioning Attribute
Genome
Metastasis Suppressor Genes
Neoplasms
Tumor Lysis Syndrome
Src Homology Domains
Gene Mutation
Whole Exome Sequencing
Genomics

Similar Papers Found In These Feeds

Precision Oncology

Precision oncology is a new approach to cancer treatment, which utilizes the molecular profiling of each tumor to develop and tailor treatment strategies to each patient. The use of these biomarkers from tumors will help to predict those who will respond to specific treatments. Here is the latest research on precision oncology.

Cancer Genomics (Keystone)

Cancer genomics approaches employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research using such technologies in this feed.

Related Papers

Biochemical Society Transactions

Mutational patterns in oncogenes and tumour suppressors

Biochemical Society TransactionsJune 11, 2016
Hanadi M BaeissaFrances M G Pearl
Cell Systems

Pan-Cancer Analysis of Mutation Hotspots in Protein Domains

Cell SystemsMay 3, 2016
Martin L MillerChris Sander
Paper Details
References
  • References
  • Citations2
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations2
1
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