Identification and characterization of new designer drug 4-fluoro-PV9 and α-PHP in the seized materials

Forensic Toxicology
Milena MajchrzakMieczysław Sajewicz

Abstract

In this study, we present identification and physicochemical characterization of new cathinone derivatives, 4-fluoro-PV9 and already known α-PHP in seized materials. Although the disclosure of α-PHP from an illegal product had been reported and characterized to some extent, the data on α-PHP are also presented together with those of 4-fluoro-PV9. The data of characterization for the two compounds were obtained by high-performance liquid chromatography (HPLC)-mass spectrometry and HPLC-diode array detection, electrospray ionization/ion trap mass spectrometry in MS(2) and MS(3) modes, gas chromatography-mass spectrometry, thermogravimetric analysis, differential scanning calorimetry, Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and nuclear magnetic resonance spectroscopy. To our knowledge, this is the first report for identification and detailed characterization of 4-fluoro-PV9 circulated on the illegal drug market.

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Citations

Jan 26, 2018·Forensic Toxicology·Milena MajchrzakMieczysław Sajewicz
Jan 2, 2021·Forensic Science International : Synergy·Nicole S Jones, Jeffrey H Comparin
Jul 25, 2017·The International Journal on Drug Policy·Svetla SlavovaVan Ingram

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Methods Mentioned

BETA
differential
nuclear magnetic resonance
NMR
differential scanning calorimetry

Software Mentioned

Xcalibur
LCQTune

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