Identification and characterization of satellite III subfamilies to the acrocentric chromosomes

Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology
Ruma BandyopadhyayL G Shaffer

Abstract

The centromeres and the short arms of the five pairs of acrocentric chromosomes in humans are composed of tandemly ordered repetitive DNA. Previous studies have suggested that the exchanges between acrocentric chromosomes have resulted in concerted evolution of different DNA sequences in their short arms. The acrocentric chromosomes are clinically relevant since they are involved in Robertsonian translocation formation and non-disjunction resulting in aneuploidy. Here we have identified seven new satellite III repetitive DNA subfamilies, determined their nucleotide sequences and established their chromosomal distributions on the short arms of the acrocentric chromosomes. Knowledge of these related sequences may help to elucidate the molecular basis of Robertsonian translocation formation.

Citations

Dec 13, 2007·Journal of Human Genetics·Sheng-Wen ShawFon-Jou Hsieh
May 17, 2014·PLoS Computational Biology·Nicolas AltemoseHuntington F Willard
Sep 10, 2013·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Massimo GiovannottiVincenzo Caputo Barucchi
Sep 3, 2014·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Malgorzata Jarmuz-SzymczakLisa G Shaffer
Oct 21, 2016·American Journal of Medical Genetics. Part a·Gilles MaussionCarl Ernst
Feb 16, 2020·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Massimo GiovannottiVincenzo Caputo Barucchi
Mar 25, 2005·Molecular Biology of the Cell·Rut ValgardsdottirGiuseppe Biamonti
May 6, 2021·International Journal of Molecular Sciences·Mariana LopesRaquel Chaves

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