Identification and quantification of bisphenol A and bisphenol B in polyvinylchloride and polycarbonate medical devices by gas chromatography with mass spectrometry

Journal of Separation Science
Pascal GimenoLaurent Lempereur

Abstract

A gas chromatography with mass spectrometry method has already been developed and published for the identification and quantification of 14 phthalates and five nonphthalate plasticizers in polyvinylchloride medical devices. In order to assay, in addition to plasticizers, bisphenols A and B possibly present in polyvinylchloride samples, this previous method was extended to the assay of these additional potential endocrine disruptors. Furthermore, as bisphenol A could also be present in polycarbonate samples, the method used for the polyvinylchloride sample was tested and validated for the assay of bisphenols A and B in polycarbonate medical devices. The separation of all compounds, including bisphenols A and B, is obtained on a cross-linked 5%-phenyl/95%-dimethylpolysiloxane capillary column using a temperature gradient. For both plastics, samples are dissolved in tetrahydrofuran followed by a precipitation of the plastic by addition of ethanol. Results obtained point out residual bisphenol A amounts for polycarbonate samples ranging from 0.6 to 0.8% and for polyvinylchloride samples less or equal to 5 ppm. No bisphenol B was detected in the samples tested. For bisphenols A and B, mean recoveries obtained on spiked polyvinylchlo...Continue Reading

References

Nov 22, 1997·The Journal of the American Dental Association·D NathansonL L Chou
Mar 10, 2001·Journal of Biomedical Materials Research·Y HaishimaA Nakamura
Jan 31, 2002·Dental Materials Journal·K SuzukiF Nishimura
Jul 26, 2003·Food Additives and Contaminants·J López-Cervantes, P Paseiro-Losada
May 4, 2005·Proceedings of the National Academy of Sciences of the United States of America·Barry G TimmsFrederick S vom Saal
May 18, 2005·Food Additives and Contaminants·B M Thomson, P R Grounds
Aug 2, 2006·Journal of Chromatography. a·Niki C MaragouMichael A Koupparis
Jan 9, 2007·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Theodore EliadesAthanasios E Athanasiou
Sep 19, 2008·JAMA : the Journal of the American Medical Association·Iain A LangDavid Melzer
Jul 25, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity·Malene BoasUlla Feldt-Rasmussen
Mar 26, 2010·Chemosphere·Sung-Hyun NamMan-Goo Kim
Jul 2, 2010·Electrophoresis·Encarnación Rodríguez-GonzaloRita Carabias-Martínez
May 25, 2011·The Journal of Steroid Biochemistry and Molecular Biology·Beverly S Rubin
Apr 18, 2012·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Elise GrignardSusanne Bremer
Sep 6, 2012·International Journal of Molecular Sciences·Sher Singh, Steven Shoei-Lung Li
Feb 1, 2014·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Pascal GimenoPierre-Antoine Bonnet

❮ Previous
Next ❯

Citations

Oct 30, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Dimitrios KloukosGeorge Eliades
Feb 14, 2017·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Cunling YeZhike Wang
Aug 26, 2020·Environmental Health Perspectives·Nate Seltenrich
Jun 2, 2017·International Journal of Genomics·Nguyen Quoc Vuong Tran, Kunio Miyake
Oct 10, 2020·Analytical Methods : Advancing Methods and Applications·Robert FrankowskiAgnieszka Zgoła-Grześkowiak
Aug 11, 2020·Chemosphere·Mikaël KedzierskiStéphane Bruzaud
Jan 19, 2018·ACS Applied Materials & Interfaces·Wei ZhuShaochen Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.