PMID: 6105177Jul 1, 1980Paper

Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite

The Journal of Pharmacy and Pharmacology
P L Williams, A C Moffat

Abstract

A delta 9-THC metabolite has been identified in human urine as an ester linked glucuronide of delta 9-THC-11-oic acid. Its identity was established by a comparison of mass spectra from the metabolite extracted from human urine and synthetically prepared material. delta 9-THC-11-oic acid glucuronide was found to be responsible for the major part of RIA cross-reactivity in urine with the Guildhay cannabinoid antiserum used in this study.

Citations

Sep 9, 2000·Forensic Science International : Synergy·W WeinmannA Bromberger
Jun 1, 1996·Journal of Clinical Forensic Medicine·A BusuttilS Bulgin
Oct 1, 1984·Journal of Psychoactive Drugs·J P Morgan
Feb 2, 2016·Drug Metabolism Reviews·Ricardo Jorge Dinis-Oliveira
Jul 1, 1983·Journal of Toxicology. Clinical Toxicology·N J WillsonE Newman
Jul 1, 1990·Forensic Science International : Synergy·A J ClatworthyM J Whitehouse
Aug 1, 1981·Journal of Clinical Pharmacology·M E Wall, M Perez-Reyes
Aug 1, 1988·Biomedical & Environmental Mass Spectrometry·R B van BreemenC Fenselau
Apr 30, 2013·Expert Opinion on Drug Metabolism & Toxicology·Radu Tanasescu, Cris S Constantinescu
Aug 23, 2007·Chemistry & Biodiversity·Marilyn A Huestis
Mar 22, 2003·Clinical Pharmacokinetics·Franjo Grotenhermen
Aug 1, 1988·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·K Bradshaw
Jul 10, 2012·Clinica Chimica Acta; International Journal of Clinical Chemistry·Karl B ScheidweilerMarilyn A Huestis

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