PMID: 6170941May 11, 1981Paper

Identification, nucleotide sequence and expression of the regulatory region of the histidine operon of Escherichia coli K-12

Nucleic Acids Research
P VerdeC B Bruni

Abstract

A restriction fragment has been isolated and its nucleotide sequence determined. This fragment contains sites for RNA polymerase binding, initiation and termination of transcription of the Escherichia coli histidine operon. In vitro transcription of plasmids containing this region generates one single histidine-specific, attenuated, small RNA: the leader RNA. This RNA is more efficiently transcribed when the template DNA is supercoiled. Another promoter was identified on the same fragment of deoxyribonucleic acid by in vitro transcription, DNA sequencing and RNA polymerase binding. Both promoters, transcribing in opposite direction, are very A-T rich and are separated by a G-C rich region containing a palyndromic structure.

References

Jan 1, 1979·Annual Review of Genetics·M Rosenberg, D Court
Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·H L YangG Zubay
Mar 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·H InokoM Imai
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·P P Di NoceraC B Bruni
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·W M Barnes
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D PiszkiewiczS M Parsons
Jan 1, 1979·Cold Spring Harbor Symposia on Quantitative Biology·J G Sutcliffe
Dec 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E B Keller, J M Calvo
Mar 1, 1978·FEBS Letters·F Sanger, A R Coulson
Jul 23, 1976·Molecular & General Genetics : MGG·K BorckN E Murray
Aug 1, 1977·Nucleic Acids Research·T A BickleR Imber
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·H M JohnstonJ R Roth

❮ Previous
Next ❯

Citations

Dec 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·N Figueroa, L Bossi
Feb 1, 1986·Journal of Biomolecular Structure & Dynamics·V BrendelE N Trifonov
Apr 25, 1983·Nucleic Acids Research·D K Hawley, W R McClure
Mar 12, 1984·Nucleic Acids Research·C Alff-Steinberger
Apr 11, 1993·Nucleic Acids Research·S Lisser, H Margalit
Oct 5, 1988·Journal of Molecular Biology·M S CarlomagnoC B Bruni
Mar 30, 2001·Fungal Genetics and Biology : FG & B·O ValeriusG H Braus
Aug 1, 2009·EcoSal Plus·Malcolm E Winkler, Smirla Ramos-Montañez
Mar 1, 1996·Microbiological Reviews·P AlifanoC B Bruni
Dec 1, 1985·Journal of Bacteriology·V GrisoliaC B Bruni
Sep 1, 1985·Journal of Bacteriology·A RiccioF Blasi
Jul 1, 1985·Journal of Bacteriology·M S CarlomagnoC B Bruni
Oct 1, 1995·Journal of Bacteriology·C A Nickerson, E C Achberger
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·M K Berlyn
Jun 12, 1987·Science·C L SmithC R Cantor

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.