PMID: 29764075May 1, 1991Paper

Identification of a contact depigmenting agent in Indian bindi

The National Medical Journal of India
A ChatierjeeS C Gupta

Abstract

Bindis, which Indian women apply on their foreheads, occasionally depigment the skin. We analysed the adhesive on bindi samples using thin layer chromatography, infrared spectrophotometry, high performance liquid chromatography and patch tested 15 patients with bindi depigmentation, 10 normal individuals and 14 patients with vitiligo. The bindi adhesive contained about 80% paratertiary butyl phenol-a depigmenting agent with a marked irritant action. Hypersensitivity to the agent did not occur. Para-tertiary butyl phenol causes depigmentation after bindi application on the forehead and we suggest that the use of this agent as an adhesive be banned.

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