PMID: 2112548Jun 1, 1990Paper

Identification of actin filaments in the rhabdomeral microvilli of Drosophila photoreceptors

The Journal of Cell Biology
K ArikawaD S Williams

Abstract

The phototransductive microvilli of arthropod photoreceptors each contain an axial cytoskeleton. The present study shows that actin filaments are a component of this cytoskeleton in Drosophila. Firstly, actin was detected in the rhabdomeral microvilli and in the subrhabdomeral cytoplasm by immunogold labeling with antiactin. Secondly, the rhabdomeres were labeled with phalloidin, indicating the presence of filamentous actin. Finally, the actin filaments were decorated with myosin subfragment-1. The characteristic arrowhead complex formed by subfragment-1 decoration points towards the base of the microvilli, so that the fast growing end of each filament is at the distal end of the microvillus, where it is embedded in a detergent-resistant cap. Each microvillus contains more than one actin filament. Decorated filaments extend the entire length of each microvillus and project into the subrhabdomeral cytoplasm. This organization is comparable to that of the actin filaments in intestinal brush border microvilli. Similar observations were made with the photoreceptor microvilli of the crayfish, Procambarus. Our results provide an indication as to how any myosin that is associated with the rhabdomeres might function.

References

Feb 1, 1989·Journal of Neurocytology·E Matsumoto-SuzukiY Hotta
Aug 17, 1989·Nature·R J Adams, T D Pollard
Oct 1, 1989·The Journal of Cell Biology·H MiyataE D Korn
Jul 1, 1987·The Journal of Cell Biology·H Saibil, E Hewat
Sep 1, 1972·Journal of Cell Science·A Forer, O Behnke
Oct 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·L G Tilney, M Mooseker
Jul 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A D BlestD S Williams
Jul 5, 1982·Journal of Molecular Biology·H R Saibil
Mar 1, 1984·The Journal of Cell Biology·H G de CouetA D Blest
Jan 1, 1982·Cell and Tissue Research·A D BlestW Eddey
Jan 1, 1980·Cell and Tissue Research·D S Williams, A D Blest

❮ Previous
Next ❯

Citations

Apr 1, 1991·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D S Williams
Feb 1, 1992·Journal of Neurocytology·G S HafnerJ Kipp
Jul 20, 2007·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Elke K BuschbeckRandy C Morgan
May 10, 2007·Pflügers Archiv : European journal of physiology·Tao Wang, Craig Montell
May 29, 2008·Cell Stress & Chaperones·Richa Arya, S C Lakhotia
May 1, 1992·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·U SchraermeyerH Stieve
Jul 1, 1994·Visual Neuroscience·J Feng, A Fein
Jan 1, 1996·Visual Neuroscience·C King-Smith, T W Cronin
Aug 5, 2005·Visual Neuroscience·Aria M MillerLaura J Robles
Feb 2, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Nicholas W RobertsThomas W Cronin
Jan 28, 2004·The Journal of Cell Biology·Andrew C Zelhof, Robert W Hardy
Mar 8, 1994·The Journal of Comparative Neurology·J J FengA Fein
Apr 14, 2012·Trends in Neurosciences·Craig Montell
Oct 16, 2007·Current Opinion in Neurobiology·Elisabeth Knust
Feb 11, 2014·Scientific Reports·Gaurav AhujaSigrun I Korsching
Oct 26, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Mélisande RichardElisabeth Knust
May 5, 2011·Developmental Neurobiology·Hongai Xia, Donald F Ready
Sep 3, 2011·Developmental Biology·Anne GalyAngela Giangrande
Aug 4, 1998·Current Opinion in Neurobiology·C Montell
Jul 1, 2008·Current Biology : CB·Akiko K SatohDonald F Ready
Sep 19, 2014·PLoS Genetics·Jing NieAndrew C Zelhof
Oct 19, 1999·Microscopy Research and Technique·A S DePina, G M Langford
Jan 24, 2002·The Journal of Biological Chemistry·Antonio RiccioMenelas N Pangalos
Apr 4, 2003·The Journal of Biological Chemistry·Shigeru KomabaMitsuo Ikebe

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.