PMID: 6401562Feb 5, 1983Paper

Identification of adverse reactions to new drugs. III: Alerting processes and early warning systems

British Medical Journal
G R Venning

Abstract

The process of discovery for 18 important adverse drug reactions was analysed in terms of study designs and other features which determined whether published reports of suspected adverse reactions were convincing or provided valid evidence of causality. First alerts were almost always anecdotal reports. For earlier alerting during clinical trials event recording is needed, associated with dose-response data and the use of patients as their own controls.

Citations

Oct 31, 1991·Klinische Wochenschrift·J F KappE Schöpf
Oct 20, 1989·Pharmaceutisch Weekblad. Scientific Edition·U Bergman
Feb 16, 2006·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·T Behrens, W Ahrens
Jan 1, 1984·Social Science & Medicine·A Melville
Mar 24, 1984·British Medical Journal·M D Rawlins
Aug 31, 1996·BMJ : British Medical Journal·T C EgbertsH G Leufkens
Jul 3, 2004·BMJ : British Medical Journal·Bruno H Ch Stricker, Bruce M Psaty
Jan 15, 2010·Annual Review of Public Health·Robert D GibbonsJ John Mann
Feb 1, 2002·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Dolors CapellàJoan-Ramon Laporte
May 15, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Nicole MittmannNeil H Shear
Jan 15, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Janice K BushThomas Hassall
Nov 1, 1987·Medical Toxicology and Adverse Drug Experience·J McEwen
Jul 1, 1987·Medical Toxicology and Adverse Drug Experience·G R Venning
Mar 1, 1992·Journal of Clinical Epidemiology·U Bergman
Jan 1, 1987·Scandinavian Journal of Gastroenterology·D S Rampton
Dec 4, 2014·World Journal of Gastroenterology : WJG·Scott Tenner
Jan 1, 1988·Drug Intelligence & Clinical Pharmacy·S A Edlavitch
Jul 3, 2007·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Toine C G Egberts
Jul 1, 1986·Medical Toxicology·J L Carson, B L Strom

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.