Identification of antigenically distinct populations of Leishmania (Viannia) guyanensis from Manaus, Brazil, using monoclonal antibodies

Acta Tropica
Gustavo Adolfo Sierra RomeroJeffrey J Shaw

Abstract

Eighty Leishmania isolates from patients who contracted cutaneous leishmaniasis in the Manaus region, Amazonas State, Brazil, were identified as Leishmania (Viannia) guyanensis by the electrophoretic profiles of six enzymes. None reacted with the species-specific monoclonal antibody B19. Two L. (V.) guyanensis subpopulations were detected with the monoclonals B2 and B12. The lack of B19 expression by the L. (V.) guyanensis strains in the present study contrasts with that of the vast majority of the strains of the same parasite from eastern Amazonia and French Guyana that express the epitope.

References

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Citations

Nov 13, 2010·Parasitology Research·Leila Ines Camara CoelhoSinval Pinto Brandão Filho
Jan 19, 2011·Transactions of the Royal Society of Tropical Medicine and Hygiene·H A BachaV S Amato
Jan 8, 2009·International Journal of Dermatology·Wendy F van der MeideRudy F M Lai A Fat
Aug 26, 2006·Tropical Medicine & International Health : TM & IH·Anna Christina Tojal da SilvaGustavo Adolfo Sierra Romero
Sep 16, 2015·PLoS Neglected Tropical Diseases·Lilian Motta CantanhêdeRicardo de Godoi Mattos Ferreira
Nov 1, 2015·Memórias do Instituto Oswaldo Cruz·Giselle Aparecida Fagundes-SilvaAlda Maria Da-Cruz
Dec 18, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Lucas Pantoja GonçalvesPatrícia Karla Santos Ramos

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