PMID: 6166008Apr 1, 1981Paper

Identification of antigenically related polypeptides at centrioles and basal bodies

Proceedings of the National Academy of Sciences of the United States of America
W LinH Kasamatsu

Abstract

An antigen localized at the centriolar region has been identified by indirect immunofluorescence studies in African green monkey kidney, human, hamster, rat, and mouse cells. The antigen consists of two polypeptides of 14,000 and 17,000 daltons. A related antigen is also present at the basal body region in ciliated cells from chicken, cat, mouse, pig, steer, and rabbit trachea and from rabbit fimbria. Immunoelectron microscopy shows that the immunoreactive antigen is indeed located in the region around the basal bodies of ciliated cat tracheal cells. Thus, we have found an antigen that is common to a variety of cell types from many different animal sources and is specifically associated with both centrioles and basal bodies. The possible role of the antigen in differentiation is discussed.

Citations

Jan 1, 1997·Cell Motility and the Cytoskeleton·S GeimerK F Lechtreck
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W Steffen, R W Linck
Nov 1, 1986·The Journal of Cell Biology·P R SagerR D Berlin
May 30, 2008·Frontiers in Bioscience : a Journal and Virtual Library·Robert J Kolb, Surya M Nauli
Jan 1, 1991·Cellular Signalling·H Sakai, K Ohta
Jan 1, 1985·Cell and Tissue Research·B P Fung, H Kasamatsu

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