Identification of characteristics of overt myocarditis in adult patients with idiopathic inflammatory myopathies

Cardiovascular Diagnosis and Therapy
Yingxian LiuZhenyu Liu

Abstract

Myocarditis is a rare complication of idiopathic inflammatory myopathies (IIMs), which is usually underestimated because of limited applications of endomyocardial biopsy and cardiovascular magnetic resonance (CMR) in clinical routines. From January 2014 to January 2019, 62 patients with initial untreated IIMs were enrolled, including 31 cases with myocarditis (case group) and 31 cases without cardiac involvement (control group). Myocarditis secondary to IIMs was defined based on definitions of IIMs. All medical data were retrieved from electrical medical records of PUMCH. The differences between two groups in symptoms, serum levels of cardiac troponin I (cTnI), creatine kinase-isozyme and N-terminal pro-brain natriuretic peptide (NT-proBNP) were analyzed. The comparisons of arrhythmia, left ventricular ejection fraction (LVEF) and restrictive diastolic dysfunction between two groups were conducted in the analysis of electrocardiogram and electrocardiogram. Besides, CMR data were analyzed to explore the characteristics of CMR in the identification of myocarditis. Meanwhile, 31 patients with myocarditis were divided into two subgroups based on the activity of anti-mitochondrial antibody M2 (AMA-M2), and the differences between tw...Continue Reading

Citations

Oct 30, 2020·Internal Medicine·Fumihiko TakahashiNaoyuki Hasebe
Jun 30, 2021·Clinical Rheumatology·Lixi ZhangUNKNOWN Chinese Rheumatism Data Center-Myositis Registry (CRDC-MYO)

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