Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis

Chinese Medicine
Wing-Fai YeungYan-Yee Ho

Abstract

Chinese medicine (CM) syndrome (zheng) differentiation is based on the co-occurrence of CM manifestation profiles, such as signs and symptoms, and pulse and tongue features. Insomnia is a symptom that frequently occurs in major depressive disorder despite adequate antidepressant treatment. This study aims to identify co-occurrence patterns in participants with persistent insomnia and major depressive disorder from clinical feature data using latent tree analysis, and to compare the latent variables with relevant CM syndromes. One hundred and forty-two participants with persistent insomnia and a history of major depressive disorder completed a standardized checklist (the Chinese Medicine Insomnia Symptom Checklist) specially developed for CM syndrome classification of insomnia. The checklist covers symptoms and signs, including tongue and pulse features. The clinical features assessed by the checklist were analyzed using Lantern software. CM practitioners with relevant experience compared the clinical feature variables under each latent variable with reference to relevant CM syndromes, based on a previous review of CM syndromes. The symptom data were analyzed to build the latent tree model and the model with the highest Bayes in...Continue Reading

References

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Citations

May 22, 2020·The American Journal of Chinese Medicine·Meng LiuFeng Li
May 2, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Yanghui GuChuan Zou

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Software Mentioned

Lantern
LTA

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