PMID: 10507225Oct 3, 1999Paper

Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea

The Korean Journal of Parasitology
T S YongH S Park

Abstract

Non-biting midges are known to contain potent inhalant allergens. IgE antibody responses to the crude extract of Chironomus kiiensis adults, a dominant chironomid species in Korea, were examined. With the IgE-ELISA or passive cutaneous anaphylaxis reactions, increased levels of chironomid-specific IgE were detected in the skin test positive human sera, or immunized BALB/c mouse sera with the crude extract adsorbed to alum. IgE-immunoblot analysis showed major IgE-reacting protein band patterns, which reacted with more than 50% of the skin test positive human sera, at 110, 80, 73, 46, 40, 37, 34, and 31 kDa. The reactive band patterns were largely similar between skin test positive humans and immune BALB/c mice. However, the bands of 55, 31, 27, 26, 24, and 23 kDa were found only in sensitized humans, but not in immunized mice.

References

Dec 1, 1987·The Journal of Allergy and Clinical Immunology·G MazurX Baur
Oct 1, 1995·International Archives of Allergy and Immunology·A M WittemanR C Aalberse

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Citations

Feb 17, 2015·International Journal for Parasitology·Juan González-FernándezCarmen Cuéllar
Aug 12, 2015·ZooKeys·Gizelle AmoraVanderly Andrade-Souza
Nov 4, 2009·The Korean Journal of Parasitology·Tai-Soon Yong, Kyoung Yong Jeong

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