Identification of degradation products of thiram in water, soil and plants using LC-MS technique

Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Bina GuptaPrem Dureja

Abstract

In order to evaluate the deleterious effects of exposure to pesticides on a target population, a comprehensive study on their degradation in the various segments of ecosystem under varying environmental conditions is needed. In view of this, a study has been carried out on the metabolic pathways of thiram, a dithiocarbamate fungicide, in a variety of matrices namely water and soil under controlled conditions and plants in field conditions. The identification of degradation products was carried out in samples collected at various time points using LC-MS. The degradation products identified can be rationalized as originating by a variety of processes like hydrolysis, oxidation, N-dealkylation and cyclization. As a result of these processes the presence of some metabolites like dimethyl dithiocarbamate, bis(dimethyl carbamoyl) disulphide, bis(dimethyl dithiocarbamoyl) trisulphide and N-methyl-amino-dithiocarbamoyl sulphide was observed in all the cases. However, some different metabolites were observed with the change in the matrix or its characteristics such as cyclised products 2(N, N-dimethyl amino)thiazoline carboxylic acid and 2-thioxo-4-thiazolidine were observed only in plants. The investigations reflect that degradation in...Continue Reading

References

Dec 20, 1999·Journal of Agricultural and Food Chemistry·S KodamaA Matsunaga
Aug 19, 2007·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Baljit SinghAtul Gupta
Apr 6, 2011·Biomedical Chromatography : BMC·Bina GuptaRahul Kumar

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Citations

Feb 6, 2018·Environmental Science and Pollution Research International·Manviri Rani, Uma Shanker
Sep 5, 2017·Water, Air, and Soil Pollution·Dorota Adamczyk-SzabelaWojciech M Wolf
Jun 8, 2018·Environmental Science and Pollution Research International·Manviri Rani, Uma Shanker
Oct 13, 2021·Scientific Reports·Dorota Adamczyk-SzabelaWojciech M Wolf

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