PMID: 9002103Jan 1, 1997Paper

Identification of febrile neonates unlikely to have bacterial infections

The Pediatric Infectious Disease Journal
C H ChiuM J Bullard

Abstract

A prospective study was undertaken to evaluate the usefulness of low risk criteria for identifying febrile neonates unlikely to have bacterial infections, particularly bacteremia and meningitis. Using these criteria we wished to check whether these low risk neonates can be safely managed as inpatients under close observation but without receiving empiric antibiotic therapy. We conducted a prospective study of 250 consecutive infants 28 days of age or less (range, 4 to 28 days) who had rectal temperatures of at least 38 degrees C. After a complete history, physical examination and sepsis workup, the 131 febrile neonates with clinical and laboratory findings indicating low risk for bacterial infections were hospitalized, closely observed and not given antibiotics. The low risk criteria used to identify these neonates included well appearance; absence of physical signs of an ear, eye or soft tissue infection; a white blood cell count of 5000 to 15,000/mm3, a neutrophil band form count of < 1500/mm3, a spun urine specimen that had < 10 white blood cells per high power field on microscopy and a C-reactive protein value of < 20 mg/l. The remaining 119 febrile neonates who did not meet the low risk criteria were hospitalized and given...Continue Reading

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Citations

Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Liliana SimonJacques Lacroix
Apr 16, 1998·The Pediatric Infectious Disease Journal·C H Chiu, T Y Lin
Dec 2, 2009·The Pediatric Infectious Disease Journal·Silvia BressanLiviana Da Dalt
Jan 3, 2012·The Pediatric Infectious Disease Journal·Silvia GarciaJavier Benito
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Dec 22, 2010·Scandinavian Journal of Infectious Diseases·Efraim BilavskyGilat Livni
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Dec 1, 2009·Emergency Medicine Clinics of North America·Ilene Claudius, Larry J Baraff
Oct 24, 2007·Emergency Medicine Clinics of North America·Paul Ishimine
Apr 1, 2006·Pediatric Clinics of North America·Paul Ishimine
Apr 6, 2002·Clinics in Laboratory Medicine·P Joanne Cornbleet
Oct 13, 2015·Revista chilena de pediatría·Benigno Miguel Méndez Espinola, Patricio Herrera Labarca
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May 5, 2017·The Pediatric Infectious Disease Journal·Lior CarmonShalom Ben-Shimol
Aug 7, 2019·Global Pediatric Health·Winston WuCourtney Mann
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Nov 30, 2000·Annals of Emergency Medicine·L J Baraff
Jan 29, 2014·Pediatrics·Shabnam JainEvaline A Alessandrini

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