Identification of genetic differences between two Campylobacter jejuni strains with different colonization potentials

Microbiology
If H AhmedD G Newell

Abstract

The consumption of poultry meat contaminated with Campylobacter jejuni is considered to be a risk factor for human campylobacteriosis. The development of targeted strategies to control campylobacters in broilers would benefit from knowledge of those bacterial factors important in colonization of the avian gut. During preliminary studies it was noted that C. jejuni NCTC 11168 was a poorer colonizer of chickens than strain 81116. This poor colonization could not be fully restored by in vivo passage, suggesting that it was a genetically endowed property of strain 11168. As the genome sequence is available for this strain, the technique of subtractive hybridization was used to identify gene fragments of strain 81116 not present in strain 11168. After two screening cycles, 24 out of 42 clones were identified as having DNA inserts specific for strain 81116. Six of these 24 clones contained gene fragment inserts with similarities to restriction-modification enzymes found in other bacteria. Two inserts had similarity to arsenic-resistance genes, whereas four others had similarities to cytochrome c oxidase III, dTDP-glucose 4,6-dehydratase, gamma-glutamyl transpeptidase and an abortive phage-resistance protein. At least some of these ge...Continue Reading

References

Jul 2, 1977·British Medical Journal·M B Skirrow
Nov 1, 1989·Journal of Bacteriology·E C ChangG R Willsky
Mar 1, 1988·The Journal of Infectious Diseases·R E BlackM J Blaser
May 1, 1987·Journal of Medical Microbiology·T PangW K Chang
Sep 1, 1985·The Journal of Infectious Diseases·J A KorlathR A Robinson
Feb 5, 1983·Lancet·S R PalmerJ L Penner
Dec 1, 1994·FEMS Microbiology Reviews·C CervantesS Silver
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jan 5, 2000·Microbes and Infection·T M Wassenaar, M J Blaser
Jan 8, 2000·Poultry Science·G Gupta, S Charles
Sep 16, 2000·Trends in Microbiology·R Lan, P R Reeves
Jan 4, 2001·Journal of Clinical Microbiology·K E DingleM C Maiden
May 26, 2001·Applied and Environmental Microbiology·D G NewellG Mead

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Citations

Feb 13, 2009·Expert Review of Proteomics·Nichollas E Scott, Stuart J Cordwell
Feb 2, 2016·Veterinary Immunology and Immunopathology·Colin PielstickerSilke Rautenschlein
Dec 25, 2015·SpringerPlus·Hana TriguiSebastien P Faucher
Nov 26, 2003·Microbiology and Immunology·Byeonghwa JeonSangryeol Ryu
Dec 23, 2006·Risk Analysis : an Official Publication of the Society for Risk Analysis·Lailai ChenPeter Teunis
Feb 22, 2005·Journal of Microbiological Methods·L M FriisJ M Wells
May 10, 2005·International Journal of Food Microbiology·A Martínez-Rodriguez, B M Mackey
Mar 26, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Joana RevezMarja-Liisa Hänninen
Jul 1, 2011·Veterinary Research·David HermansFrank Pasmans
Oct 18, 2014·Frontiers in Cellular and Infection Microbiology·Dirk Hofreuter
Feb 3, 2007·FEMS Immunology and Medical Microbiology·Boy M BachtiarBenjamin N Fry
Aug 23, 2006·FEMS Microbiology Letters·Erica S RinellaDeborah S Threadgill
Oct 1, 2005·FEMS Microbiology Letters·Tohru TakataMartin J Blaser
Jun 16, 2016·Frontiers in Microbiology·Manuel J Saint-CyrNabila Haddad
Dec 6, 2008·World Journal of Gastroenterology : WJG·Rune AabenhusAsa Ljungh
Dec 1, 2017·PloS One·Christina BronowskiUNKNOWN ENIGMA Consortium
Mar 21, 2013·Foodborne Pathogens and Disease·Alexandre ThibodeauAnn Letellier
Oct 30, 2012·Journal of Bacteriology·Joana RevezMarja-Liisa Hänninen
Oct 1, 2013·Applied and Environmental Microbiology·Sophie KittlerGünter Klein
Apr 19, 2006·Avian Diseases·Katrine Nørrelund KnudsenMogens Madsen
Mar 4, 2005·The Journal of Antimicrobial Chemotherapy·A Pratt, V Korolik
Feb 27, 2004·The Journal of Biological Chemistry·Catherine D CarrilloChristine M Szymanski
Jul 25, 2006·Infection and Immunity·Dirk HofreuterJorge E Galán
Jan 15, 2008·Applied and Environmental Microbiology·Rebecca A WeingartenJonathan W Olson
Oct 6, 2005·Applied and Environmental Microbiology·T J W M Van GerweJ A P Heesterbeek
Jun 9, 2009·Applied and Environmental Microbiology·Liping WangQijing Zhang

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