Identification of hepatitis C virus in the common bed bug - a potential, but uncommon route for HCV infection?

Emerging Microbes & Infections
Jiaxin LingJohn H-O Pettersson

Abstract

During an ongoing virome metagenomics project we identified hepatitis C virus (HCV) in a pool of recently blood-fed common bed bug (Cimex lectularius) nymphs sampled from domestic residences in Europe. Additional PCR and genomic analysis revealed that the virus was a member of HCV genotype 3A, one of the most prevalent genotypes in Europe. Although the role of the common bed bug in the transmission of human hepatitis viruses remains unclear, our study suggests that it merits additional investigation.

References

Apr 2, 2009·JAMA : the Journal of the American Medical Association·Jerome Goddard, Richard deShazo
Jun 16, 2009·Emerging Infectious Diseases·Pascal DelaunayOlivier Chosidow
Feb 4, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pascal DelaunayPhilippe Brouqui
Jan 11, 2012·Clinical Microbiology Reviews·Stephen L DoggettRichard C Russell
Aug 24, 2013·PLoS Pathogens·Zach N AdelmanKevin M Myles
Jul 30, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jane P MessinaEleanor Barnes
Jun 14, 2016·Archives of Dermatological Research·Olivia LaiJared Jagdeo
Jan 28, 2017·Scientific Reports·Michiru NishitaYasuhiro Minami
Mar 9, 2019·BMC Infectious Diseases·John H-O PetterssonKathrine Stene-Johansen

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Datasets Mentioned

BETA
MT254535
PRJNA613931

Methods Mentioned

BETA
PCR

Software Mentioned

Bowtie2
Trinity
MAFFT
Diamond
FigTree
blastn

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