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Identification of human CD4+ T cell populations with distinct antitumor activity

bioRxiv

Jan 2, 2020

Michelle H NelsonChrystal M Paulos

Abstract

How naturally arising human CD4+ T helper subsets impact tumor immunity is unknown. We reported that human CD4+CD26high T cells elicit potent immunity against solid tumor malignancies. As CD26high T cells secrete type-17 cytokines and have been categorized as Th17 cells, we posited thes...read more

Mentioned in this Paper

Tumor Immunity
T-helper Cell Type 2
Th17 Cells
Curative Treatment
Solid Tumour
CD8-Positive T-Lymphocytes
T-helper Cell Type 1
Cytokine
T-Lymphocyte
CD4 Positive T Lymphocytes
30
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Identification of human CD4+ T cell populations with distinct antitumor activity

bioRxiv

Jan 2, 2020

Michelle H NelsonChrystal M Paulos

DOI: 10.1101/2019.12.31.891317

Abstract

How naturally arising human CD4+ T helper subsets impact tumor immunity is unknown. We reported that human CD4+CD26high T cells elicit potent immunity against solid tumor malignancies. As CD26high T cells secrete type-17 cytokines and have been categorized as Th17 cells, we posited thes...read more

Mentioned in this Paper

Tumor Immunity
T-helper Cell Type 2
Th17 Cells
Curative Treatment
Solid Tumour
CD8-Positive T-Lymphocytes
T-helper Cell Type 1
Cytokine
T-Lymphocyte
CD4 Positive T Lymphocytes
30

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