Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (oryzias latipes)

Endocrinology
Shinji KandaYoshitaka Oka

Abstract

Recently, a novel physiologically active peptide, kisspeptin (metastin), has been reported to facilitate sexual maturation and ovulation by directly stimulating GnRH neurons in several mammalian species. Despite its importance in the neuroendocrine regulation of reproduction, kisspeptin neurons have only been studied in mammals, and there has been no report on the kisspeptin or kisspeptin neuronal systems in nonmammalian vertebrates. We used medaka for the initial identification of the KiSS-1 gene and the anatomical distribution of KiSS-1 mRNA expressing neurons (KiSS-1 neurons) in the brain of nonmammalian species. In situ hybridization for the medaka KiSS-1 gene cloned here proved that two kisspeptin neuronal populations are localized in the hypothalamic nuclei, the nucleus posterioris periventricularis and the nucleus ventral tuberis (NVT). Furthermore, NVT KiSS-1 neurons were sexually dimorphic in number (male neurons > female neurons) under the breeding conditions. We also found that the number of KiSS-1 neurons in the NVT but not that in the nucleus posterioris periventricularis was positively regulated by ovarian estrogens. The fact that there were clear differences in the number of NVT KiSS-1 neurons between the fish un...Continue Reading

References

Aug 11, 1987·Brain Research·C R Wirsig, C M Leonard
Apr 1, 1986·General and Comparative Endocrinology·M KobayashiI Hanyu
Dec 1, 1985·The Journal of Clinical Endocrinology and Metabolism·H H GohS S Ratnam
May 22, 1995·The Journal of Comparative Neurology·M H KimK Aida
Aug 24, 1999·European Journal of Pharmacology·M A López-PatiñoN de Pedro
Aug 24, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Y K NarnawareR E Peter
Jan 2, 2003·Progress in Brain Research·Yoshitaka Oka
Aug 29, 2003·Proceedings of the National Academy of Sciences of the United States of America·Nicolas de RouxEdwin Milgrom
Oct 24, 2003·The New England Journal of Medicine·Stephanie B SeminaraWilliam H Colledge
Dec 4, 2003·Biochemical and Biophysical Research Communications·Sandrine FunesEric L Gustafson
Jun 29, 2004·Biochemical and Biophysical Research Communications·Hisanori MatsuiTetsuya Ohtaki
Jan 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Sophie MessagerSamuel A J R Aparicio
Feb 3, 2005·Proceedings of the National Academy of Sciences of the United States of America·Muhammad ShahabTony M Plant
May 28, 2005·Endocrinology·Jeremy T SmithRobert A Steiner
Sep 22, 2005·The Journal of Clinical Endocrinology and Metabolism·Waljit S DhilloStephen R Bloom
Mar 1, 2006·Journal of Neuroendocrinology·T NakamachiS Shioda
Apr 6, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Jeremy T SmithRobert A Steiner
Jun 10, 2006·Molecular and Cellular Endocrinology·M L GottschR A Steiner
Aug 12, 2006·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·Hiroshi Kawauchi

❮ Previous
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Citations

Nov 19, 2013·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Na Na KimCheol Young Choi
Jul 28, 2011·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Yann Le PageOlivier Kah
May 15, 2008·Proceedings. Biological Sciences·Timothy J GreivesGregory E Demas
Oct 19, 2012·Proceedings. Biological Sciences·Towako HirakiKataaki Okubo
Aug 29, 2012·Reproductive Biology and Endocrinology : RB&E·Sethu SelvarajMichiya Matsuyama
Sep 23, 2009·Endocrine Reviews·Amy E OakleyRobert A Steiner
Nov 19, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Hyun Suk ShinCheol Young Choi
Dec 26, 2008·Human Reproduction Update·A K Roseweir, R P Millar
Apr 24, 2013·Animal Science Journal = Nihon Chikusan Gakkaihō·Hiroaki OkamuraYoshihiro Wakabayashi
Jun 13, 2013·General and Comparative Endocrinology·Nerine T JosephRobert P Millar
Feb 26, 2016·Fish Physiology and Biochemistry·Huayu SongQuanqi Zhang
Oct 24, 2012·General and Comparative Endocrinology·Takashi Kitahashi, Ishwar S Parhar
Sep 13, 2012·General and Comparative Endocrinology·Satoshi Ogawa, Ishwar S Parhar
Aug 14, 2012·General and Comparative Endocrinology·Hironori AndoAtsuhiko Hattori
May 23, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·M CowanH Migaud
Jun 12, 2012·Progress in Neurobiology·Ishwar ParharTakashi Kitahashi
Apr 28, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Alejandro S MechalyFrancesc Piferrer
Dec 6, 2011·General and Comparative Endocrinology·Manuel Tena-SempereManuel Carrillo
Feb 24, 2010·Frontiers in Neuroendocrinology·John Godwin
Oct 28, 2015·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Ashis SahaShiba Shankar Giri
Aug 19, 2009·General and Comparative Endocrinology·B Levavi-SivanJ J Lareyre
Sep 25, 2014·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Hirofumi OhgaMichiya Matsuyama
May 16, 2009·General and Comparative Endocrinology·Geir Lasse TarangerTom Hansen
Apr 28, 2009·General and Comparative Endocrinology·Yonathan ZoharOlivier Kah
Sep 27, 2008·Peptides·Abigail Elizur
Sep 6, 2008·Peptides·Manuel Tena-Sempere, Hubert Vaudry
Jul 23, 2008·Peptides·Michelle L GottschRobert A Steiner
Jul 29, 2008·Molecular and Cellular Endocrinology·Jason T PopeskuVance L Trudeau
Feb 4, 2009·Journal of Neuroendocrinology·P E ChappellK L Latham
May 22, 2009·Annals of the New York Academy of Sciences·M CarrilloA Gómez

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