Identification of Mycobacterium tuberculosis and non-tuberculous mycobacteria from cutaneous sarcoidosis lesions by reverse blot hybridization assay

The Journal of Dermatology
Hanil LeeEung Ho Choi

Abstract

While the etiology of sarcoidosis remains uncertain, mycobacteria have been suggested as a causative infectious agent. To investigate the causal relationship between mycobacteria and sarcoidosis, we performed a reverse blot hybridization assay (REBA) to identify mycobacteria from the skin samples of nine patients with sarcoidosis. Six of the nine samples were shown to be positive for mycobacteria by REBA, including Mycobacterium tuberculosis and non-tuberculous mycobacteria. This is the first study to identify mycobacteria from the skin samples of sarcoidosis patients using REBA, and our results could strengthen the etiologic association between mycobacteria and sarcoidosis.

References

Sep 3, 1999·Journal of Cutaneous Pathology·N LiJ Bhawan
Jun 1, 2007·The European Respiratory Journal·D GuptaS K Jindal
Apr 30, 2013·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·J MunkhdelgerK H Park
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May 10, 2016·Tuberculosis·Rupesh AgrawalCarlos Pavesio
Nov 30, 2016·BMC Pulmonary Medicine·Tiago EstevesVicente Garcia-Patos

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Citations

Mar 4, 2020·Journal of Cutaneous Pathology·Taro IsohisaNorito Katoh
Jul 18, 2020·Frontiers in Immunology·Marc A Judson
Sep 30, 2020·Respiratory Medicine·Silvia LeeGirish Dwivedi
Aug 8, 2021·Diagnostics·Thomas El JammalPascal Sève

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