Identification of optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection: potential role of a Combination Antibiogram

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Mari MizutaEbbing Lautenbach

Abstract

To better determine the optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection, we evaluated the utility of a novel combination antibiogram. Although the combination antibiogram allowed modest fine-tuning of choices for dual antibiotic therapy, selections based on the 2 antibiograms did not differ substantively. Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a beta-lactam.

References

Nov 1, 1987·Reviews of Infectious Diseases·S D HolmbergP A Blake
Apr 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M P WeinsteinL B Reller
Apr 9, 1998·The Journal of Antimicrobial Chemotherapy·G BonfiglioG Nicoletti
Dec 10, 1998·Journal of Internal Medicine·L LeiboviciS D Pitlik
Jul 18, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A C FluitF J Schmitz
Jun 9, 2004·Diagnostic Microbiology and Infectious Disease·Erika J ErnstBradley N Doebbeling

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Citations

Sep 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David L Paterson
Jun 13, 2009·The Journal of Antimicrobial Chemotherapy·Ali A El Solh, Ahmad Alhajhusain
May 9, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Deverick J AndersonRichard Drew
Apr 5, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jason M PogueDaryl D DePestel
Jul 16, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anucha Apisarnthanarak, Linda M Mundy
Jan 9, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jennifer ChristoffStephen G Weber
May 10, 2015·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Zachary R SmithFrank P Tverdek
Apr 18, 2018·Therapeutic Advances in Infectious Disease·Matthew SongRamy H Elshaboury
Dec 16, 2016·Clinical Microbiology Reviews·Philippe Morency-PotvinRobert A Weinstein
Aug 5, 2010·Critical Care Medicine·Tejal N GandhiLaraine L Washer
Sep 20, 2011·Pharmacotherapy·Kristi A TraugottJames S Lewis

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