PMID: 11900980Mar 20, 2002Paper

Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells

Mechanisms of Development
Masatake SatoToru Nakano

Abstract

The gene expression patterns of primordial germ cells (PGCs) and embryonic stem cells were analyzed by a modified serial analysis of gene expression. During the process, we cloned a novel gene, PGC7, which was preferentially expressed in PGCs. Immunohistochemical analysis revealed that PGC7 was specifically expressed in early pre-implantation embryos, PGCs and oocytes. These results suggest that PGC7 might play an important role in the development of PGCs and oocytes.

References

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