Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine

Biochemical and Biophysical Research Communications
M M Billah, J M Johnston

Abstract

Human amniotic fluid and fetal urine were examined for the presence of phospholipid platelet-activating factor (PAF). PAF was detected in lipid extracts of some samples of amniotic fluid obtained from women in labor but it was undetectable in samples of amniotic fluid obtained before the onset of labor. PAF was identified by chromatographic mobility, platelet aggregation and chemical modifications. LysoPAF was also present in amniotic fluid at higher concentrations than those of PAF. Both PAF and lysoPAF were identified also in newborn and adult urine.

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Citations

Jun 1, 1997·Archives of Pharmacal Research·S Y SonH W Chang
Oct 24, 1986·Biochimica Et Biophysica Acta·D R HoffmanJ M Johnston
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