Identification of plant defence regulators through transcriptional profiling of Arabidopsis thaliana cdd1 mutant

Journal of Biosciences
Swadhin SwainAshis K Nandi

Abstract

A sustainable balance between defence and growth is essential for optimal fitness under pathogen stress. Plants activate immune response at the cost of normal metabolic requirements. Thus, plants that constitutively activate defence are deprived of growth. Arabidopsis thaliana mutant constitutive defence without defect in growth and development1 (cdd1) is an exception. The cdd1 mutant is constitutive for salicylic acid accumulation, signalling, and defence against biotrophic and hemibiotrophic pathogens, without having much impact on growth. Thus, cdd1 offers an ideal genetic background to identify novel regulators of plant defence. Here we report the differential gene expression profile between cdd1 and wild-type plants as obtained by microarray hybridization. Expression of several defence-related genes also supports constitutive activation of defence in cdd1. We screened T-DNA insertion mutant lines of selected genes, for resistance against virulent bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pst DC3000). Through bacterial resistance, callose deposition and pathogenesis-associated expression analyses, we identified four novel regulators of plant defence. Resistance levels in the mutants suggest that At2g19810 a...Continue Reading

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Citations

Oct 28, 2015·International Journal of Molecular Sciences·Weiping FangXiaojie Yang
May 31, 2019·The Plant Journal : for Cell and Molecular Biology·Feng Y CaoDarrell Desveaux
Jan 13, 2018·Molecular Plant-microbe Interactions : MPMI·Nidhi SinghAshis Kumar Nandi
Jan 24, 2018·Journal of Biosciences·Mrunmay Kumar GiriAshis Kumar Nandi
Oct 2, 2021·Physiologia Plantarum·Janesh Kumar GautamAshis Kumar Nandi

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