Identification of quantitative trait loci controlling symptom development during viral infection in Arabidopsis thaliana

Molecular Plant-microbe Interactions : MPMI
O SicardV Decroocq

Abstract

In compatible interactions between plants and viruses that result in systemic infection, symptom development is a major phenotypic trait. However, host determinants governing this trait are mostly unknown, and the mechanisms underlying it are still poorly understood. In a previous study on the Arabidopsis thaliana-Plum pox virus (PPV) pathosystem, we showed a large degree of variation in symptom development among susceptible accessions. In particular, Cvi-1 (Cape Verde islands) accumulates viral particules but remains symptomless, Col-0 (Columbia) sometimes shows weak symptoms compared with Ler (Landsberg erecta), which always shows severe symptoms. Genetic analyses of Col x Ler and Cvi x Ler F2 and recombinant inbred line (RIL) populations suggested that symptom development as well as viral accumulation traits are polygenic and quantitative. Three of the symptom quantitative trait loci (QTL) identified could be confirmed in near-isogenic lines, including PSI1 (PPV symptom induction 1), which was identified on the distal part of chromosome 1 in both RIL populations. With respect to viral accumulation, several factors have been detected and, interestingly, in the Col x Ler population, two out of three viral accumulation QTL colo...Continue Reading

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Citations

Jul 4, 2012·Molecular Plant-microbe Interactions : MPMI·Ping XuMarilyn J Roossinck
Apr 4, 2012·Expert Opinion on Drug Discovery·Chunmei JinHyun Park
Oct 25, 2011·Molecular Plant Pathology·Karen-Beth G ScholthofGary D Foster
Jun 17, 2014·The Plant Journal : for Cell and Molecular Biology·Laurence OuibrahimCarole Caranta
Oct 10, 2013·Molecular Plant Pathology·Juan Antonio GarcíaThierry Candresse
Jul 6, 2014·Molecular Plant Pathology·Manuel RubioPedro Martínez-Gómez
Feb 5, 2014·Trends in Plant Science·Mohamed El-SodaMark G M Aarts

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