PMID: 6160876Jun 13, 1980Paper

Identification of ribonuclease P activity from chick embryos

Biochimica Et Biophysica Acta
E J Bowman, S Altman

Abstract

RNAase P (EC 3.1.26.5) activity has been identified in chick embryo thigh tissue on the basis of specific cleavage of Escherichia coli 129 nucleotide tRNATyr precursor and has been partially purified by the procedure used for human tissue culture KB cell RNAase P. RNAase P from chick resembles the KB cell RNAase P in substrate specificity, requirement for a divalent cation (Mg2+) and a monovalent cation (K+, Na+ or NH4+) for activity, inhibition by bulk tRNA, ready inactivation by proteases, and increasing instability; with purification. RNAase P activity is also present in whole chick embryos, as well as in liver and heart tissues. Furthermore, crude preparations of RNAase P from chick embryo heart tissue are relatively free of contaminating nucleases.

References

Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·B C StarkS Altman
Aug 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R Kole, S Altman
Sep 1, 1972·Archives of Biochemistry and Biophysics·G PieczenikM L Gefter
May 11, 1973·Molecular and Cellular Biochemistry·S Altman, H D Robertson

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Citations

Jan 1, 1984·CRC Critical Reviews in Biochemistry·M P Deutscher
Aug 23, 2008·Conservation Biology : the Journal of the Society for Conservation Biology·Innocent B RwegoTony L Goldberg
Mar 24, 2000·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·R S SingerD C Hirsh

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