Identification of Rickettsia felis DNA in the blood of domestic cats and dogs in the USA.

Parasites & Vectors
Md Monirul HoqueChengming Wang

Abstract

The main vector and reservoir host of Rickettsia felis, an emerging human pathogen causing flea-borne spotted fever, is the cat flea Ctenocephalides felis. While cats have not been found to be infected with the organism, significant percentages of dogs from Australia and Africa are infected, indicating that they may be important mammalian reservoirs. The objective of this study was to determine the presence of R. felis DNA in the blood of domestic dogs and cats in the USA. Three previously validated PCR assays for R. felis and DNA sequencing were performed on blood samples obtained from clinically ill domestic cats and dogs from 45 states (2008-2020) in the USA. The blood samples had been submitted for the diagnosis of various tick-borne diseases in dogs and feline infectious peritonitis virus, feline immunodeficiency virus, and Bartonella spp. in cats. Phylogenetic comparisons were performed on the gltA nucleotide sequences obtained in the study and those reported for R. felis and R. felis-like organisms. Low copy numbers of R. felis DNA (around 100 copies/ml whole blood) were found in four cats (4/752, 0.53%) and three dogs (3/777, 0.39%). The very low levels of infection in clinically ill animals is consistent with R. felis ...Continue Reading

References

Sep 1, 1994·Journal of Medical Entomology·M E SchrieferA F Azad
Apr 23, 2005·Veterinary Research·Philippe ParolaDidier Raoult
Jul 11, 2006·Journal of Clinical Microbiology·José A OteoValvanera Ibarra
Feb 6, 2007·Journal of Feline Medicine and Surgery·Jennifer R HawleyMichael R Lappin
Apr 11, 2008·Vector Borne and Zoonotic Diseases·Kevin R MacalusoLane D Foil
Sep 9, 2008·Veterinary Parasitology·Yihang LiBernhard Kaltenboeck
Sep 13, 2008·Journal of Feline Medicine and Surgery·Danielle B BaylissMichael R Lappin
Aug 4, 2009·Journal of Medical Entomology·Kathryn E Reif, Kevin R Macaluso
May 27, 2011·Vector Borne and Zoonotic Diseases·Sze Fui HiiRebecca J Traub
Jul 5, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P Parola
Aug 3, 2014·Parasites & Vectors·Ferran SeguraMaría-Mercedes Nogueras
Dec 17, 2014·BMC Infectious Diseases·Jilei ZhangChengming Wang
Dec 30, 2014·EcoHealth·Jesús Alonso Panti-MayRaúl Tello-Martín
May 9, 2016·Trends in Parasitology·Emmanouil AngelakisDidier Raoult
Sep 28, 2016·The Lancet Infectious Diseases·Philippe ParolaDidier Raoult
Mar 10, 2017·Ticks and Tick-borne Diseases·Nicole StephensonJanet Foley
Jun 6, 2018·The American Journal of Tropical Medicine and Hygiene·Oleg MediannikovDidier Raoult
Apr 13, 2019·Parasites & Vectors·Lavel Chinyama MoongaJunya Yamagishi
Apr 25, 2019·Veterinary Parasitology : Regional Studies and Reports·Pornkamol PhoosangwalthongTawin Inpankaew
Jul 16, 2019·Vector Borne and Zoonotic Diseases·Jilei ZhangChengming Wang
Apr 25, 2020·Emerging Microbes & Infections·Subarna BaruaChengming Wang

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Methods Mentioned

BETA
PCR
PCRs
FRET

Software Mentioned

CLUSTALW

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