PMID: 6104986Jun 23, 1980

Identification of shellfish fatty acids and their effects on lipogenic enzymes

Biochimica Et Biophysica Acta
N IritaniM Morita

Abstract

The fatty acids which are common to and characteristic of shellfish, were identified by mass spectrometry and NMR spectral analyses as being: octadecatetraenoioc acid, eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid. When the fatty acids isolated by high performance liquid chromatography were separately intubated into rats, hepatic glucose-6-phosphate dehydrogenase (EC 1.1.1.49), malic enzyme (EC 1.1.1.40) and acetyl-CoA carboxylase (EC 6.4.1.2) were reduced more effectively as compared with linoleic acid intubation. These enzymes were reduced most markedly by eicosapentaenoic acid-intubation. The fatty acids seem to be effective components in reduction of triacylglycerol and lipogenic enzyme levels in rats fed on shellfish.

Citations

Sep 1, 1991·The British Journal of Nutrition·P F MohanM P Cleary
Sep 1, 1991·Medical Hypotheses·P Singer, E Richter-Heinrich
Apr 25, 2000·Metabolism: Clinical and Experimental·P MarmillotM R Lakshman
Aug 1, 1997·Toxicology and Applied Pharmacology·N Kudo, Y Kawashima
Dec 1, 1988·Scandinavian Journal of Clinical and Laboratory Investigation·T A Hagve, B O Christophersen
Mar 1, 1982·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·S H GoodnightD R Illingworth
Jul 13, 2006·Current Opinion in Lipidology·William S Harris, Deepti Bulchandani
May 1, 1995·Journal of Dairy Science·J N SpainB A Watkins
Apr 15, 1992·European Journal of Biochemistry·N Iritani

Related Concepts

Parinaric acid, (all-E)-isomer
Docosapentaenoic acid, (all Z)-isomer
Acetyl-CoA Carboxylase
Metazoa
Docosahexaenoic Acid, Sodium Salt
Eicosanoic Acids
Fatty Acids, Unsaturated
Glucosephosphate Dehydrogenase
Ligase
Liver

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