PMID: 2498499May 1, 1989Paper

Identification of the cause of separation (creaming) of lipid emulsions in intravenous infusion

Journal of Pediatric Gastroenterology and Nutrition
J M RattenburyC J Taylor

Abstract

Over a 2-month period, white deposits were found in infusion sets delivering parenteral nutrition mixtures that included a lipid emulsion. When components of the infusion were mixed in the laboratory, separation (creaming) of the emulsion could be demonstrated, and this enabled us to predict the concentrations of the prescribed infusates that were likely to cream. Further investigations showed that creaming occurred when the lipid emulsion was mixed with heparin and calcium ions at concentrations above 1 U/ml and 1 mumol/ml, respectively.

Citations

Nov 29, 2005·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·James A CattonDermot Burke
Feb 26, 2000·Clinics in Perinatology·G Putet
Jul 17, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Mark G Klang
Feb 18, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Joseph I BoullataUNKNOWN American Society for Parenteral and Enteral Nutrition
Mar 1, 1994·JPEN. Journal of Parenteral and Enteral Nutrition·S H ErdmanB B Grill
Jan 19, 2000·JPEN. Journal of Parenteral and Enteral Nutrition·D F DriscollB R Bistrian
May 1, 1995·The Journal of Pathology·G Hulman
Jan 1, 1991·Critical Reviews in Biochemistry and Molecular Biology·E Palecek
Jan 1, 1997·Annales Françaises D'anesthèsie Et De Rèanimation·J P Estèbe

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