PMID: 10894752Jul 14, 2000

Identification of the Escherichia coli nicotinic acid mononucleotide adenylyltransferase gene

Journal of Bacteriology
R A MehlT P Begley

Abstract

The gene (ybeN) coding for nicotinate mononucleotide adenylyltransferase, an NAD(P) biosynthetic enzyme, has been identified and overexpressed in Escherichia coli. This enzyme catalyzes the reversible adenylation of nicotinate mononucleotide and shows product inhibition. The rate of adenylation of nicotinate mononucleotide is at least 20 times faster than the rate of adenylation of nicotinamide mononucleotide.

References

Feb 25, 2003·Protein Expression and Purification·Monica EmanuelliGiulio Magni
Apr 26, 2003·Current Opinion in Chemical Biology·Andrei L Osterman, Ross Overbeek
Jul 27, 2002·Journal of Bacteriology·Svetlana Y GerdesAndrei L Osterman
Nov 26, 2002·Journal of Bacteriology·Oleg V KurnasovAndrei L Osterman
Oct 27, 2016·Molecular Microbiology·Timothy J BrickmanSandra K Armstrong
Nov 6, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jee-Hyun KimDirk Schnappinger
Jun 27, 2017·Molecular Cell·Nadezda SedlyarovaEvgeny Nudler
Oct 31, 2017·Applied Biochemistry and Biotechnology·Xueying WangZongbao K Zhao

Citations

Jul 1, 1983·Journal of Bacteriology·K T HughesB M Olivera
Dec 24, 1997·Journal of Bacteriology·Nadia RaffaelliGiulio Magni
Sep 10, 1999·The Journal of Biological Chemistry·A GeerlofW V Shaw
Feb 12, 2008·Current Protocols in Molecular Biology·S Tabor

Related Concepts

Alkalescens-Dispar Group
Nicotinamide Mononucleotide
nicotinic acid ribonucleotide
Metabolic Inhibition
Catalysis
nicotinate mononucleotide
Nicotinate-nucleotide adenylyltransferase
Nicotinamide-Nucleotide Adenylyltransferase
Escherichia coli
Anabolism

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