Mar 1, 1991

Identification of the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation

American Heart Journal
Akiko Suyama ChishakiM Nakamura

Abstract

We continuously observed successive pairs of R-R intervals during atrial fibrillation and hypothesized that the shortest R-R interval for a given preceding R-R interval in a pair represents the functional refractory period of the atrioventricular node at that preceding interval. To test this hypothesis we simulated atrial fibrillation in 28 isolated cross-perfused canine hearts and obtained an R-R interval scatterplot by plotting the R-R intervals as a function of the immediately preceding R-R interval. This scatterplot enabled us to detect a series of the shortest R-R intervals for a wide range of preceding R-R intervals, and this allowed us to estimate the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation. The estimated functional refractory periods correlated well with those measured by the conventional method (r = 0.93). We conclude that the proposed method makes it possible to estimate the rate-dependent functional refractory periods of the atrioventricular node in atrial fibrillation.

Mentioned in this Paper

Left Bundle Branch of His
Perfusion
Refractory Period, Electrophysiological
Atrial Fibrillation
Refractory Period
Body Surface Area Formula for Dogs
Structure of Atrioventricular Node
Entire Atrioventricular Node
Cardiac Pacing, Artificial
Dog family

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