Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance.

Journal of Bacteriology
Javier López-GarridoJosep Casadesús

Abstract

The damX gene product of Salmonella enterica serovar Typhimurium is a protein located in the inner membrane. DamX migrates as a 70-kDa protein in SDS-PAGE even though the predicted protein size is 46 kDa. Synthesis of DamX protein occurs in both exponential- and stationary-phase cultures. Disruption of damX causes severe sensitivity to bile. Lack of the outer membrane protein AsmA suppresses bile sensitivity in Salmonella damX mutants.

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Citations

Mar 1, 2012·Applied and Environmental Microbiology·Anita KhatiwaraYoung Min Kwon
Jan 26, 2012·PLoS Genetics·Sara B HernándezJosep Casadesús
Oct 1, 2011·Environmental Microbiology Reports·Andreas J BäumlerJosep Casadesús
Oct 22, 2011·Microbiology·Avelino Álvarez-OrdóñezColin Hill
Feb 18, 2011·Gut Microbes·Javier López-Garrido, Josep Casadesús
Dec 6, 2019·Nature Communications·Martín AlcorloJuan A Hermoso
Mar 28, 2019·Scientific Reports·Verónica UrdanetaJosep Casadesús
Dec 23, 2020·Nature Microbiology·Caisey V PulfordJay C D Hinton
Mar 16, 2021·Frontiers in Microbiology·Rocío Fernández-FernándezJosep Casadesús
Apr 2, 2021·PLoS Computational Biology·Spencer J MitchellChris Bailey-Kellogg

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