PMID: 8939161Nov 1, 1996Paper

Identification of unique peanut and soy allergens in sera adsorbed with cross-reacting antibodies

The Journal of Allergy and Clinical Immunology
P A EigenmannH A Sampson

Abstract

Soybean and peanut are members of the legume family and share several common antigenic fractions. Patients allergic to one of these foods have serum IgE antibodies that immunologically cross-react with other legumes. Nevertheless, ingestion of other legumes generally does not induce an allergic reaction, suggesting that cross-reacting antibodies are not clinically relevant. This study was designed to identify unique peanut or soybean antigenic fractions, with sera adsorbed to remove cross-reacting antibodies, thus resulting in sera with IgE antibodies unique to either soy or peanut. Cross-reacting antibodies to soy were removed from the sera of two patients allergic to peanut and soy and three patients allergic to peanut by soy-affinity chromatography. Cross-reacting antibodies to peanut were adsorbed from the sera of a patient allergic to peanut and soy and a patient allergic to peanut by peanut-affinity chromatography. Adequate removal of cross-reacting antibodies was verified by ELISA after each adsorption step. Unadsorbed sera and sera adsorbed to remove cross-reacting antibodies (either to soy or to peanut) were assayed for specific IgE binding to peanut or soy immunoblots. Unique peanut-specific IgE antibodies (i.e., soy ...Continue Reading

References

Jul 1, 1990·The Journal of Allergy and Clinical Immunology·H A Sampson
Nov 1, 1985·The Journal of Pediatrics·H A Sampson, C C McCaskill
Jan 1, 1981·The Journal of Allergy and Clinical Immunology·M I SachsJ W Yunginger

❮ Previous
Next ❯

Citations

Dec 22, 1999·Clinical Reviews in Allergy & Immunology·J S Stanley, G A Bannon
Nov 17, 2010·Plant Foods for Human Nutrition·Cinzia BallabioMarcello Duranti
May 5, 2012·Clinical Reviews in Allergy & Immunology·Alok Kumar VermaPremendra D Dwivedi
Apr 7, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·UNKNOWN American College of Allergy, Asthma, & Immunology
Nov 26, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Amy M Scurlock, A Wesley Burks
Jun 20, 2000·Allergy·S H SichererA W Burks
Jul 30, 2002·Allergy·Elide A PastorelloA M Robino
Nov 8, 2002·The New England Journal of Medicine·S Paul Kuwayama, Hugh A Sampson
Nov 16, 2004·Critical Reviews in Food Science and Nutrition·E N Clare MillsPeter R Shewry
Nov 24, 1998·Allergy·H A Sampson
Feb 18, 1999·The Journal of Clinical Investigation·P RabjohnG A Bannon
Aug 28, 2015·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N MaruyamaM Ebisawa
Oct 12, 2010·Regulatory Toxicology and Pharmacology : RTP·David RouquiéCorinne Hérouet-Guicheney
Jan 6, 2009·Regulatory Toxicology and Pharmacology : RTP·Ovidiu IvanciucWerner Braun
Feb 6, 2007·Immunology and Allergy Clinics of North America·Anna Nowak-Wegrzyn
Aug 30, 2008·Molecular Nutrition & Food Research·Justin MarshPeter R Shewry
Jul 27, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·María PedrosaSantiago Quirce
Jun 9, 1999·The Journal of Allergy and Clinical Immunology·H A Sampson
Oct 16, 1999·The Journal of Allergy and Clinical Immunology·D A Moneret-VautrinM Morisset
Jun 16, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·María PedrosaSantiago Quirce
Jun 16, 2015·Clinical and Translational Allergy·Georgios RentzosEsbjörn Telemo
Oct 12, 2016·Allergologia et immunopathologia·M N KimJ W Park
Dec 13, 2006·Methods : a Companion to Methods in Enzymology·Jonathan D de JongeHenk van Loveren
Jul 30, 2002·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Philippe A Eigenmann
Sep 30, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Karolin KernMichael Szardenings
Jan 27, 1999·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·P A Eigenmann, H A Sampson
Mar 14, 2008·Molecular Nutrition & Food Research·Evelien L van BoxtelHarry Gruppen
Jun 23, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S A LewisJ O'B Hourihane
Jul 5, 2005·Molecular Nutrition & Food Research·Sander R PiersmaStef J Koppelman
Jan 26, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·F GizzarelliR Tinghino
Dec 21, 2012·Expert Review of Vaccines·Darren S MillerJohn D Hayball
Jul 5, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Moon SenGary A Bannon
Aug 29, 1998·Allergy·W BurksG A Bannon
Sep 6, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M P de LeonC Suphioglu
Apr 29, 2004·The Journal of Nutrition·Christopher T Cordle
Sep 1, 2019·Comprehensive Reviews in Food Science and Food Safety·Faisal ShahJinchuang Zhang
Apr 1, 2007·Comprehensive Reviews in Food Science and Food Safety·Hsiao-Wei WenRichard A Durst

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

International Archives of Allergy and Immunology
Tom A BeardsleeJ P Markwell
Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
R K BushJ A Nordlee
© 2021 Meta ULC. All rights reserved