PMID: 9179265May 1, 1997Paper

Identification of women with T1-T2 breast cancer at low risk of positive axillary nodes

Journal of Surgical Oncology
D A FeinB L Eisenberg

Abstract

The diagnostic and therapeutic significance of axillary dissection has been questioned. We sought to define a subgroup of patients with early-stage breast cancer who are at low risk for positive axillary nodes. Between 1970 and 1995, 1,598 women with stage I and II breast cancer underwent level I-II axillary dissection with a minimum of 10 nodes removed. The following factors were examined in univariate analysis for predicting positive nodes: race, method of detection, location of the primary tumor, age, menopausal status, obesity, ER status, PR status, pathologic tumor size, lymphatic vascular invasion, tumor grade, and histology. Four hundred and forty-five of the 1,598 patients (27.8%) had histologically positive axillary nodes. Significant factors in univariate analysis for positive nodes included: tumor size, lymphatic vascular invasion, grade, method of detection, primary tumor location, and age. The only group of women with a 0% risk of axillary nodes were those in whom the pathologic tumor size was < or = 5 mm and mammographically detected. A 5-10% risk of positive axillary nodes was identified in women with (1) pathologic tumor size 6-10 mm, mammographically detected, and age < or = 40 years, and (2) tubular carcinoma ...Continue Reading

References

Jan 1, 1977·British Journal of Haematology·J Palek
Jul 1, 1991·International Journal of Radiation Oncology, Biology, Physics·B L FowbleR L Goodman
Jan 1, 1990·Clinical Oncology : a Journal of the Royal College of Radiologists·G G RibeiroS S Banerjee
Feb 1, 1989·Annals of Surgery·J G TinnemansH H De Boer
May 1, 1989·American Journal of Surgery·V RegerP C Jolly
Feb 1, 1988·International Journal of Radiation Oncology, Biology, Physics·L J SolinR L Goodman
May 20, 1972·British Medical Journal·H AtkinsA B Wayte
Dec 1, 1969·Annals of Surgery·H R Butcher
Dec 1, 1969·Annals of Surgery·C D Haagensen, E Cooley
Jan 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·P BucalossiC Cantù
Dec 1, 1994·American Journal of Clinical Oncology·K J HalversonC Rush
Aug 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P P LinR R Baker
Apr 1, 1993·The British Journal of Surgery·J WallsR E Mansel

❮ Previous
Next ❯

Citations

Jul 27, 2004·Annals of Surgery·Sebastian F SchoppmannUNKNOWN Austrian Breast and Colorectal Cancer Study Group
Oct 20, 2006·International Journal of Radiation Oncology, Biology, Physics·Sunanda PejavarBruce G Haffty
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology
Mar 29, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L WeirI A Olivotto
Jun 20, 2001·The British Journal of Surgery·G PapadatosJ Boyages
Jul 11, 2006·Breast Cancer Research and Treatment·Joan E CunninghamTommy E Cupples
Jan 26, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·U VeronesiP Maisonneuve
Sep 24, 1999·Annals of Surgical Oncology·G B MannK J Van Zee
Dec 18, 2004·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Koji Arihiro
Nov 25, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·G YoshimuraQ Yang
Jan 1, 2010·Indian Journal of Surgical Oncology·Rajshekhar C JakaR V Parameswaran
Sep 6, 2005·Breast Cancer Research and Treatment·Timothy SullivanAlphonse G Taghian
Jan 13, 2006·Annals of Surgical Oncology·S David NathansonMichael Linden
Mar 3, 2012·Updates in Surgery·Ali Cihat YildirimHulagu Kargici
Aug 24, 2011·Annals of Surgical Oncology·Bijan AnsariJudy C Boughey
Jul 13, 2013·Annals of Surgical Oncology·Tiffany TorstensonJudy C Boughey
Jun 12, 2010·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Erin I LewisPriscilla J Slanetz
Jan 8, 1999·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·F K BöhlerW Rhomberg
Jan 5, 2002·Journal of the National Cancer Institute. Monographs·S J Schnitt
Jun 25, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Diego PérezAntonio Rueda
Mar 6, 1999·Breast Cancer Research and Treatment·Y Y Chen, S J Schnitt
Mar 22, 2002·ANZ Journal of Surgery·B ChuaJ Boyages

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Lobular

Lobular carcinoma is an invasive type of breast cancer in which lobules, areas of the breast that produce milk, undergo malignant transformation. Here is the latest research.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.