Identifying a possible factor for the increased newborn size in singleton pregnancies after assisted reproductive technology using cryopreserved embryos, in comparison with fresh embryos

Reproductive Medicine and Biology
Rena IshiiYuji Taketani

Abstract

To determine whether the cycle regimens that are used for endometrial preparation are associated with the birthweight (BW) after assisted reproductive technology (ART) using frozen-thawed embryo transfer (FET). The BW of singletons who were born by ART using FET was compared retrospectively, according to whether a FET was conducted in a hormone replacement therapy cycle (HRT, n = 403) or an ovulatory cycle (OVL, n = 117). The BW after timed intercourse (NAT, n = 162) also was investigated. There were no significant differences in the age of the mothers, percentage of primiparas, gestational periods, Body Mass Index, and sex ratio between the HRT and OVL cycles. The average BW from HRT was significantly greater than that of OVL. The BW from HRT was also greater, compared with NAT, while statistical significance was not achieved between OVL and NAT. The putative factors affecting the BW, such as ovarian stimulation protocols, endometrial thickness, and the stage and quality of embryos, could not explain the difference in the BW between the HRT and OVL cycles. An increased BW from ART using FET seems to be ascribable to conditions of the endometrium, but not cryopreservation procedures per se, which might provide a mechanistic fra...Continue Reading

References

Aug 1, 1984·Fertility and Sterility·G H ZeilmakerA C Drogendijk
Apr 11, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·L Deligdisch
Jun 17, 2000·Fertility and Sterility·D K GardnerW B Schoolcraft
Mar 8, 2002·The New England Journal of Medicine·Laura A SchieveLynne S Wilcox
Feb 9, 2010·Fertility and Sterility·Bengt KällénPetra Otterblad Olausson
Sep 22, 2011·Obstetrics and Gynecology·Suleena Kansal KalraKurt T Barnhart
Apr 3, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Emily L SeetMishka Terplan
Apr 27, 2012·Reproductive Sciences·Kewei ShangYoufei Guan
Feb 5, 2013·Fertility and Sterility·Laxmi A Kondapalli, Alfredo Perales-Puchalt
Feb 28, 2013·Journal of Assisted Reproduction and Genetics·Ryan J HeitmannEric A Widra
Dec 17, 2014·Fertility and Sterility·Frederick LicciardiDavid H McCulloh
May 10, 2016·Best Practice & Research. Clinical Obstetrics & Gynaecology·Terhi T Piltonen
Jan 2, 2018·American Journal of Obstetrics and Gynecology·Julia F LitzkyCarmen J Marsit

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Methods Mentioned

BETA
pregnancy test
hormone replacement therapy
Hormone

Software Mentioned

EZR
R

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