PMID: 29848240Jun 1, 2018Paper

Identifying and treating codeine dependence: a systematic review

The Medical Journal of Australia
Suzanne NielsenJacinta L Johnson

Abstract

Codeine dependence is a significant public health problem, motivating the recent rescheduling of codeine in Australia (1 February 2018). To provide information for informing clinical responses, we undertook a systematic review of what is known about identifying and treating codeine dependence. Articles published in English that described people who were codeine-dependent or a clinical approach to treating people who were codeine-dependent, without restriction on year of publication, were reviewed. Articles not including empirical data were excluded. One researcher screened each abstract; two researchers independently reviewed full text articles. Study quality was assessed, and data were extracted with standardised tools. MEDLINE and EMBASE were searched for relevant publications on 22 November 2016. The reference lists of eligible studies were searched to identify further relevant publications. 2150 articles were initially identified, of which 41 were eligible for inclusion in our analysis. Studies consistently reported specific characteristics associated with codeine dependence, including mental health comorbidity and escalation of codeine use attributed to psychiatric problems. Case reports and series described codeine depend...Continue Reading

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Citations

Sep 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Łukasz Sobczak, Krzysztof Goryński
Oct 3, 2019·Addiction·Rose CairnsNicholas A Buckley
Mar 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ferenc ZádorMahmoud Al-Khrasani

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