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Identifying arsenic trioxide (ATO) functions in leukemia cells by using time series gene expression profiles

Gene

Feb 10, 2014

Hong Yan YangJingru Cui

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Abstract

Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). In order to explore the molecular mechanism of ATO in leukemia cells with time series, we adopted bioinformatics strategy to analyze expression changing patterns and ...read more

Mentioned in this Paper

Gene Expression
PTMA protein, human
Serine Hydrolase Activity
Antineoplastic Agents
PTK2B protein, human
Recombinant Interleukin-1
Positive Regulation of Cell Adhesion
Transcriptional Regulation
Tumor Cells, Malignant
Chronic Lymphocytic Leukemia
Paper Details
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  • Identifying arsenic trioxide (ATO) functions in leukemia cells by using time series gene expression profiles

    Gene

    Feb 10, 2014

    Hong Yan YangJingru Cui

    PMID: 24262935

    DOI: 10.1016/j.gene.2013.10.072

    Abstract

    Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). In order to explore the molecular mechanism of ATO in leukemia cells with time series, we adopted bioinformatics strategy to analyze expression changing patterns and ...read more

    Mentioned in this Paper

    Gene Expression
    PTMA protein, human
    Serine Hydrolase Activity
    Antineoplastic Agents
    PTK2B protein, human

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    Paper Details
    References
    • References28
    • Citations1
    • References28
    • Citations1
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