journal cover

Identifying cancer type specific oncogenes and tumor suppressors using limited size data

Journal of Bioinformatics and Computational Biology

Oct 8, 2016

Ana B Pavel, Cristian I Vasile

Abstract

Cancer is a complex and heterogeneous genetic disease. Different mutations and dysregulated molecular mechanisms alter the pathways that lead to cell proliferation. In this paper, we explore a method which classifies genes into oncogenes (ONGs) and tumor suppressors. We optimize this me...read more

Mentioned in this Paper

Biochemical Pathway
Adenocarcinoma of Lung (Disorder)
Size
The Cancer Genome Atlas
Tumor Suppressor Genes
Genome
Genes
Somatic Mutation
Metastasis Suppressor Genes
Adenocarcinoma of Colon
Paper Details
References
  • References25
  • Citations2
123

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Identifying cancer type specific oncogenes and tumor suppressors using limited size data

Journal of Bioinformatics and Computational Biology

Oct 8, 2016

Ana B Pavel, Cristian I Vasile

PMID: 27712196

DOI: 10.1142/s0219720016500311

Abstract

Cancer is a complex and heterogeneous genetic disease. Different mutations and dysregulated molecular mechanisms alter the pathways that lead to cell proliferation. In this paper, we explore a method which classifies genes into oncogenes (ONGs) and tumor suppressors. We optimize this me...read more

Mentioned in this Paper

Biochemical Pathway
Adenocarcinoma of Lung (Disorder)
Size
The Cancer Genome Atlas
Tumor Suppressor Genes
Genome
Genes
Somatic Mutation
Metastasis Suppressor Genes
Adenocarcinoma of Colon

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Colon Adenocarcinoma

Approximately 95% of all colon cancers are colon adenocarcinomas, which are associated with a significant reduction in or loss of goblet cells. Here is the latest research on colon adenocarcinomas and its treatment.

Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (copd) is a progressive respiratory disease associated with increasing morbidity and mortality worldwide.

Related Papers

BMC Systems Biology

Integrating mutation and gene expression cross-sectional data to infer cancer progression

BMC Systems BiologyJanuary 27, 2016
Julia L FleckChristos G Cassandras
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme

Oncogenes and tumor suppressor genes of human breast cancer

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzymeFebruary 1, 1993
K TakitaY Nakamura
Paper Details
References
  • References25
  • Citations2
123
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