Idiopathic congenital chylothorax presented with severe hydrops and treated with octreotide in term newborn

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Ali BulbulAsiye Nuhoglu

Abstract

Chylothorax is a relatively uncommon condition defined as an abnormal collection of lymphatic fluid within the pleural space. Morbidity of congenital chylothorax (CC) is high, and prognosis is very poor if chylothorax is associated with hydrops fetalis. The optimal treatment of CC has not been defined. Conservative treatment (low-fat high-protein diets with medium chain triglycerides, total parenteral nutrition, pleural drainage) and surgical intervention are performed. However, there is little experience with the use of octreotide therapy in this condition. We report a newborn with CC presented with severe non-immune hydrops and chylothorax resistant to mainly conservative treatment. The patient improved rapidly and the chylothorax disappeared with use of continuous administration of octreotide (10 microg/kg/per hour).

References

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Citations

Jul 27, 2010·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·F BecmeurC Scheib-Brohly
Jan 1, 2010·BMJ Case Reports·Paulo Rego SousaJosé Luis Nunes
Nov 1, 2011·Pediatrics and Neonatology·Ning-Hui FooWen-Hui Tsai
Nov 19, 2011·Acta Paediatrica·Dharmesh Shah, John K H Sinn
May 27, 2010·Pediatric Pulmonology·Ali Bulbul, Emel Kabakoglu Unsur
Mar 6, 2016·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Whitney W Brock, Wanda T Bradshaw
Nov 17, 2015·Iranian Red Crescent Medical Journal·Shahla AfsharpaimanMohammad Torkaman
Aug 16, 2016·Clinics in Chest Medicine·Maxim Itkin, Francis X McCormack
Mar 31, 2018·Journal of Paediatrics and Child Health·Carlo BelliniLuca A Ramenghi
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Animitra Das, Prakeshkumar S Shah
Dec 16, 2020·American Journal of Perinatology·Hatice S Y CömertHaluk Sarıhan
Apr 2, 2014·Pediatrics·James D Tutor

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