Idiopathic granulomatous mastitis: time to avoid unnecessary mastectomies

The Breast Journal
Kamal E Bani-HaniNawaf J Shatnawi

Abstract

Idiopathic granulomatous mastitis is a rare disease of the breast. Clinically and radiologically it may mimic breast carcinoma. Awareness of surgeons, pathologists, and radiologists is essential to avoid unnecessary mastectomies. Data regarding 24 patients with histologically confirmed idiopathic granulomatous mastitis treated at our center over 8 years were analyzed. The mean age of patients was 34.3 years. Breast lump was the most common presentation. The right breast was affected in 16 cases. Four patients were pregnant at the time of presentation. Lactation within 6 months of presentation was documented in four patients. Two patients used contraceptives pills. A clinical suspicion of malignancy was present in 17 cases. Mammography was performed in 16 patients and showed focal asymmetrical dense lesions in 9, well-circumscribed opacity in 4, spiculated lesion in 1, and was normal in 2. Fine-needle aspiration was performed in 17 patients, of which 2 were reported as malignant. Wide local excision was the mainstay of treatment. One patient underwent mastectomy upon clinical, mammographic, and repeated cytologic findings consistent with malignancy, and the final histology confirmed idiopathic granulomatous mastitis with no evid...Continue Reading

References

Aug 1, 1979·American Journal of Surgery·K L Brown, P H Tang
Jul 1, 1992·The American Journal of Medicine·M B Jorgensen, D M Nielsen
May 1, 1987·Journal of Clinical Pathology·J J GoingU Chetty
Dec 1, 1972·American Journal of Clinical Pathology·E Kessler, Y Wolloch
Oct 2, 1980·The New England Journal of Medicine·D A DeHertoghS G Economou
Apr 4, 1981·The Medical Journal of Australia·H L Carmalt, G Ramsey-Stewart
Feb 1, 1995·The British Journal of Surgery·I M SalamA J Sim
Feb 1, 1995·The Australian and New Zealand Journal of Surgery·J R MiliauskasR S Williams
Jan 1, 1997·Der Pathologe·R DialloB Dockhorn-Dworniczak
Aug 1, 1997·Japanese Journal of Clinical Oncology·S ImotoK Mukai
Jul 14, 1999·The American Journal of Surgical Pathology·S A Silver, F A Tavassoli
Aug 3, 1999·AJR. American Journal of Roentgenology·B K HanS J Nam
Mar 11, 2000·The Australian and New Zealand Journal of Surgery·C H YipM Swain
Nov 30, 2000·Obstetrics and Gynecology·J GoldbergP Park
Mar 17, 2001·Archives of Internal Medicine·J PouchotP Vinceneux
May 1, 2001·The Breast Journal·E C Gal-GombosR J Poppiti
May 12, 2001·The Breast Journal·Gábor Cserni, Károly Szajki
Jul 14, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K SchelfoutP M Buytaert
Jul 9, 2002·The Breast Journal·B CakirF Ozyilmaz
Aug 20, 2002·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Teruhisa SakuraiYoshitaka Okamura
Jan 21, 2004·The Breast : Official Journal of the European Society of Mastology·Y ErhanO Ozbal
Jan 1, 1997·Annals of Saudi Medicine·H Kfoury, L Al Bhlal

❮ Previous
Next ❯

Citations

Oct 1, 2009·Archives of Gynecology and Obstetrics·Marilin Rosa
Jan 6, 2011·Archives of Gynecology and Obstetrics·Sami AkbulutYusuf Yagmur
Dec 17, 2009·Journal of General Internal Medicine·Rakshitkumar A PatelMartin Rodriguez
Feb 15, 2013·QJM : Monthly Journal of the Association of Physicians·A NéelM Hamidou
Nov 22, 2005·The Breast Journal·Eric C H LaiHeng Tat Leong
May 11, 2006·The Breast Journal·Mangal VeerysamiPaul Carmichael
Jan 1, 2010·BMJ Case Reports·M J HwangR Vidya
Jul 31, 2007·International Seminars in Surgical Oncology : ISSO·Richard TuliAnne L Rosenberg
Oct 25, 2012·Journal of Translational Medicine·Jian-jun YuElizabeth L Y Ng
Jan 10, 2012·Diagnostic Pathology·Chih-Hsun LinJason Chou
Mar 19, 2013·BMC Research Notes·Juan A Garcia-Rodiguez, Andrew Pattullo
Oct 2, 2013·TheScientificWorldJournal·Fatih AltintoprakIhsan Hakkı Ciftci
Dec 22, 2009·Annals of Plastic Surgery·Farrah M YauNancy Van Laeken
Jul 19, 2006·World Journal of Surgery·Alper AkcanYucel Aritas
Jun 2, 2007·World Journal of Surgery·Muna M BaslaimShefaa A Al-Amoudi
Feb 2, 2016·Autoimmunity·Fereshte SheybaniZahra Mirfeizi
May 7, 2015·Asian Journal of Surgery·Mehmet VelidedeogluFatih Aydogan
Nov 27, 2014·ANZ Journal of Surgery·Anita Skandarajah, Leah Marley
Sep 18, 2012·La Revue de médecine interne·M HelloM Hamidou
Aug 5, 2011·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Michaela HladikGottfried Wechselberger
Jun 24, 2010·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·K Y Y Kok, P U Telisinghe
Jun 1, 2009·Surgical Pathology Clinics·Deborah A Dillon, Susan C Lester
Feb 26, 2015·American Journal of Therapeutics·Kashmira WankhedkarRobert Lahita
Mar 10, 2015·Obstetrics and Gynecology·Fereshte SheybaniMasoumeh Gharib
Nov 7, 2015·Journal de gynécologie, obstétrique et biologie de la reproduction·E LaasS Catteau-Jonard
Feb 19, 2009·Journal of Cutaneous Pathology·Fausto MaffiniGiuseppe Viale
Nov 13, 2008·The Breast Journal·Asiie OlfatbakhshGholamreza Esmaeeli Djavid
Sep 1, 2007·The Breast Journal·Ricka TaghizadehEva M Weiler-Mithoff
Sep 26, 2007·Annals of the New York Academy of Sciences·Uriel KatzPnina Langevitz
Mar 6, 2013·The Breast Journal·Parveen JayiaDimitri Hadjiminas
Jan 19, 2012·International Journal of Dermatology·Frederick A PereiraKaren Karsif
Nov 23, 2013·The Breast Journal·Ahmad KavianiAbbas Rabbani
Dec 25, 2009·The Breast Journal·Koray OcalKamuran Konca
May 6, 2015·The Breast Journal·Lin ChengPaolo Gattuso
Apr 14, 2016·Future Oncology·John R Benson, Dorin Dumitru
Mar 10, 2015·American Journal of Surgery·Marcia E BoutonIan K Komenaka
Mar 18, 2015·International Journal of Surgery Case Reports·Marcia E BoutonIan K Komenaka
Dec 3, 2014·International Journal of Surgery·C Gopalakrishnan NairMisha
Jun 9, 2012·Diagnostic and Interventional Imaging·Houssine BoufettalNaïma Samouh
Jul 9, 2013·Journal of the Korean Surgical Society·Sung Mo HurJeong Eon Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.