"Idiopathic" intracranial hypertension caused by venous sinus thrombosis associated with contraceptive usage

Optometry : Journal of the American Optometric Association
Marisa A PerezNorman J Schatz

Abstract

Cerebral venous sinus thrombosis (CVST) is a life-threatening condition that may present with symptoms and signs identical to idiopathic intracranial hypertension (IIH). Both conditions consist of increased intracranial pressure (ICP); however, IIH shows no evidence of contributory intracranial pathology. Oral hormonally based contraceptive usage has been associated with both conditions as well. Because disc edema often occurs in CVST, and IIH and is evident in other sight- and life-threatening conditions such as intracranial mass lesions, neuroimaging and other ancillary testing must be conducted for definitive diagnosis. An 18-year-old white woman with IIH previously diagnosed presented with headaches and severe visual loss in the left eye. Bilateral disc edema with macular edema in the left eye (O.S.) was present. Threshold perimetry found bilaterally enlarged blind spots as well as a central scotoma O.S. Her medical history was significant for a right transverse, sigmoid and jugular siphon thrombosis secondary to a hypercoagulable state and associated with her use of oral birth control medication. Subsequent magnetic resonance venography (MRV) found the presence of CVST. Despite anticoagulation therapy and acetazolamide, sh...Continue Reading

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Aug 5, 2011·European Journal of Medical Research·Dajiang WangS Wei
Apr 19, 2012·Disease-a-month : DM·Donald E GreydanusDilip R Patel
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Aug 19, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M EtminanC Sheldon

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