Idiopathic intracranial hypertension: Update on diagnosis and management.

Clinical Medicine : Journal of the Royal College of Physicians of London
Benjamin R WakerleyAlexandra J Sinclair

Abstract

Idiopathic intracranial hypertension is a condition of raised intracranial pressure of unknown cause. Features include new onset headache, which is frequently non-specific; papilloedema is present, visual disturbances are common; and there may be sixth nerve palsy. Diagnosis includes brain imaging with venography to exclude structural causes and venous sinus thrombosis. Lumbar puncture reveals pressure greater than 250 mmCSF with normal constituents. Treatments aim to modify the disease, prevent permanent visual loss and manage headaches. These include weight loss. For those with rapid visual decline, urgent surgical intervention is essential. For most, this is a chronic condition characterised by significantly disabling headaches.

References

Dec 17, 2010·Journal of Neurology·Alexandra K BallCarl E Clarke
Aug 24, 2013·Neurology·Deborah I FriedmanKathleen B Digre
Feb 15, 2014·The Journal of Headache and Pain·James T F LaiAlexandra J Sinclair
Apr 24, 2014·JAMA Neurology·Michael WallUNKNOWN NORDIC Idiopathic Intracranial Hypertension Study Group
Aug 8, 2015·Neurology·Michael WallUNKNOWN NORDIC Idiopathic Intracranial Hypertension Study Group
Aug 8, 2015·The Cochrane Database of Systematic Reviews·Rory J PiperIoannis P Fouyas
Dec 25, 2015·Lancet Neurology·Keira A MarkeyAlexandra J Sinclair
Nov 30, 2016·Practical Neurology·Stefan WilliamsRichard Davey
Jul 29, 2017·Headache·Deborah I FriedmanUNKNOWN and the NORDIC IIHTT Study Group
Aug 25, 2017·Science Translational Medicine·Hannah F BotfieldAlexandra J Sinclair
Jun 15, 2018·Cephalalgia : an International Journal of Headache·William J ScottonAlex J Sinclair
Jun 16, 2018·Journal of Neurology, Neurosurgery, and Psychiatry·Susan P MollanAlexandra J Sinclair
Jun 19, 2018·Cephalalgia : an International Journal of Headache·Andreas YiangouAlexandra J Sinclair
Jul 10, 2018·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Catherine HornbyAlexandra J Sinclair
Aug 30, 2018·Practical Neurology·Susan P MollanAlexandra J Sinclair
Oct 6, 2018·BMJ : British Medical Journal·Susan P MollanDavid J Nicholl
Oct 26, 2018·Eye·Susan P MollanAlexandra J Sinclair
Dec 15, 2018·Current Opinion in Neurology·Susan P MollanAlexandra J Sinclair
Jan 18, 2019·British Journal of Neurosurgery·Anna BjornsonMatthew Garnett
Mar 14, 2019·Current Opinion in Neurology·James L MitchellAlexandra J Sinclair
Jul 6, 2019·Practical Neurology·Benjamin R Wakerley

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Citations

Sep 17, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Paul Morrish
May 19, 2021·Journal of Neurology·Heather Angus-LeppanRoberto J Guiloff
Jul 6, 2021·The Egyptian Journal of Neurology, Psychiatry and Neurosurgery·Mumen Abdalazim DafallahMohammed Izzadden
Aug 7, 2021·Life·Rigmor Højland JensenDagmar Beier

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