Idiopathic normal pressure hydrocephalus: results of a prospective cohort of 236 shunted patients

Acta Neurochirurgica. Supplement
Maria Antonia PocaJuan Sahuquillo

Abstract

To describe the outcomes and complication rates in 236 patients with idiopathic normal pressure hydrocephalus (INPH) after treatment. Among a cohort of 257 patients with suspected INPH, 244 were shunted and 236 were followed up at 6 months after shunting (145 men [61.4%] and 91 women [38.6%] with a median age of 75 years). The study protocol of these patients included clinical, radiological, neuropsychological and functional assessment. The decision to shunt patients was based on continuous intracranial pressure monitoring and CSF dynamics studies. A differential low-pressure valve system, always combined with a gravity compensating device, was implanted in 99% of the patients. After shunting, 89.9% of the patients showed clinical improvement (gait improved in 79.3% of patients, sphincter control in 82.4%, and dementia in 63.7%). Two patients (0.8%) died. Early postsurgical complications were found in 13 of the 244 shunted patients (5.3%). Six months after shunting, the follow-up CT showed asymptomatic hygromas in 8 of the 236 (3.4%). Additional postsurgical complications were found in 7 patients (3%), consisting of 6 subdural hematomas (3 acute and 3 chronic) and 1 distal catheter infection. Currently, a high percentage of pat...Continue Reading

Citations

Apr 20, 2017·Acta neurochirurgica·Simon D ThompsonL D Watkins
Jan 9, 2017·Neurologia i neurochirurgia polska·Stefanie KaestnerWolfgang Deinsberger
Apr 1, 2016·Journal of Alzheimer's Disease : JAD·Anne M KoivistoVille Leinonen
Nov 4, 2015·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·I A Shamov
Mar 1, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Asem Salma
Mar 25, 2017·Physiotherapy Theory and Practice·Zachary RethornEmily Gavlick

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