Idiopathic pericarditis and pericardial effusion in children: contemporary epidemiology and management

Journal of the American Heart Association
Divya ShaktiJane W Newburger

Abstract

Multicenter studies on idiopathic or viral pericarditis and pericardial effusion (PPE) have not been reported in children. Colchicine use for PPE in adults is supported. We explored epidemiology and management for inpatient hospitalizations for PPE in US children and risk factors for readmission. We analyzed patients in the Pediatric Health Information System database for (1) a code for PPE; (2) absence of codes for underlying systemic disease (eg, neoplastic, cardiac, rheumatologic, renal); (3) age ≥30 days and <21 years; and (4) discharge between January 1, 2007, and December 31, 2012, from 38 hospitals contributing complete data for each year of the study period. Among 11 364 hospitalizations with PPE codes during the study period, 543 (4.8%) met entry criteria for idiopathic or viral PPE. Significantly more boys were noted, especially among adolescents. No temporal trends were noted. Median age was 14.5 years (interquartile range 7.3 to 16.6 years); 78 patients (14.4%) underwent pericardiocentesis, 13 (2.4%) underwent pericardiotomy, and 11 (2.0%) underwent pericardiectomy; 157 (28.9%) had an intensive care unit stay, including 2.0% with tamponade. Median hospitalization was 3 days (interquartile range 2 to 4 days). Medicat...Continue Reading

References

Jan 10, 2002·The Journal of Thoracic and Cardiovascular Surgery·Kathy J JenkinsLisa I Iezzoni
Jul 31, 2003·Cardiology in the Young·Geoffrey Chi Fung Mok, Samuel Menahem
Aug 23, 2003·Journal of the American College of Cardiology·Marja RaatikkaEero V Jokinen
May 4, 2004·European Heart Journal·Bernhard MaischUNKNOWN Task Force on the Diagnosis and Management of Pricardial Diseases of the European Society of Cardiology
Aug 30, 2005·The American Journal of Cardiology·Massimo ImazioRita Trinchero
May 16, 2007·Circulation·Massimo ImazioRita Trinchero
May 22, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sylvia Frisancho-KissDelisa Fairweather
Aug 4, 2007·Pediatric Cardiology·B KühnR E Breitbart
Jun 30, 2011·Pediatric Emergency Care·Savithiri RatnapalanLee Benson
Aug 30, 2011·Annals of Internal Medicine·Massimo ImazioUNKNOWN CORP (COlchicine for Recurrent Pericarditis) Investigators
Jul 26, 2012·Circulation. Cardiovascular Quality and Outcomes·Sunil J GhelaniDarren Klugman
Sep 3, 2013·The New England Journal of Medicine·Massimo ImazioUNKNOWN ICAP Investigators

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Citations

Mar 24, 2016·Current Cardiology Reports·Alexander FardmanYehuda Adler
Apr 17, 2016·Archives of Disease in Childhood·Samer AlabedAmanda Burls
Apr 6, 2018·BMC Pediatrics·Yu-Lin KangGuang-Hua Zhu
Jan 26, 2016·Journal of Cardiovascular Medicine·Massimo ImazioYehuda Adler
Jun 21, 2020·Current Cardiology Reports·Enrico TombettiCarla Carnovale
Oct 18, 2019·Yeungnam University Journal of Medicine·Ju Hee ShinHee Joung Choi
Apr 11, 2018·Internal and Emergency Medicine·Antonio BrucatoDomenico Prisco
Nov 5, 2019·Frontiers in Pediatrics·Enrico TombettiRolando Cimaz
Sep 3, 2020·Pediatrics in Review·Gal Barbut, Joshua P Needleman
Jan 3, 2019·Pediatrics in Review·Hari TunuguntlaSusan W Denfield
Feb 17, 2021·Pediatric Cardiology·Faith MyersGurumurthy Hiremath
Aug 2, 2020·Jornal de pediatria·Stasa KrasicVladislav Vukomanovic
Jul 10, 2021·Frontiers in Pediatrics·Paulina Lubocka, Robert Sabiniewicz

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