Idiopathic thrombocytopenic purpura following successful treatment of acute lymphoblastic leukemia

Leukemia & Lymphoma
N M Tannir, Hagop Kantarjian

Abstract

Thrombocytopenia is common in patients with acute lymphocytic leukemia (ALL) at diagnosis. It is a universal side effect of dose-intensive regimens employed in the treatment of adult ALL. In patients with ALL who achieve remission, thrombocytopenia frequently indicates relapse. We report three adult patients successfully treated for ALL who developed thrombocytopenia and were found to have immune-mediated thrombocytopenia (ITP). Possible pathophysiologic mechanisms underlying the association of ALL and ITP are discussed.

References

Jan 1, 1979·American Journal of Hematology·K HassidimJ Morrison
Jan 1, 1991·The American Journal of Pediatric Hematology/oncology·A S CorneliusM Poncz
Oct 1, 1993·European Journal of Haematology·J K Campbell, C A Mitchell
Feb 2, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H M KantarjianE J Freireich

❮ Previous
Next ❯

Citations

Oct 12, 2005·Journal of Pediatric Hematology/oncology·Jean-Marie AndréYves Bertrand
May 9, 2006·Journal of Pediatric Hematology/oncology·A Emin KurekciOkan Ozcan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.